Lung Cancer Clinical Trial

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Erlotinib Is Being Studied With Or Without An Investigational Drug, PF-02341066, In Patients With Lung Cancer

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Summary

This is a Phase 1/2 study comparing the safety and anti-tumor activity of erlotinib alone versus erlotinib in combination with PF-02341066 in patients with advanced non-small cell lung cancer.

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Eligibility Criteria

Inclusion Criteria:

histologically proven diagnosis of Non-Small Cell Lung Cancer (NSCLC) that is locally advanced or metastatic and of the adenocarcinoma subtype (including mixed adenosquamous histology)
evident disease progression by Response Evaluation Criterion in Solid Tumors (RECIST) after at least one but no more than 2 chemotherapy regimens for advanced disease
tumors must have measurable disease as per RECIST

Exclusion Criteria:

known interstitial lung disease
prior treatment with an agent that is known or proposed to be active by action on EGFR tyrosine kinase or c-Met/HGF (Phase 2 Portion)

Study is for people with:

Lung Cancer

Phase:

Phase 1

Estimated Enrollment:

27

Study ID:

NCT00965731

Recruitment Status:

Completed

Sponsor:

Pfizer

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There are 13 Locations for this study

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University of Alabama at Birmingham
Birmingham Alabama, 35233, United States
University of Alabama at Birmingham
Birmingham Alabama, 35294, United States
University of California, Irvine Medical Center Pharmacy
Orange California, 92868, United States
University of California, Irving - Medical Center
Orange California, 92868, United States
University of California Irvin
Orange California, 92868, United States
Holy Cross Hospital
Fort Lauderdale Florida, 33308, United States
Siteman Cancer Center -West County
Creve Coeur Missouri, 63141, United States
Barnes-Jewish Hospital
St. Louis Missouri, 63110, United States
Washington University, School of Medicine
St. Louis Missouri, 63110, United States
Siteman Cancer Center
St. Peters Missouri, 63376, United States
OSU East
Columbus Ohio, 43205, United States
The Ohio State University James Cancer Hospital
Columbus Ohio, 43210, United States
James Care in Kenny
Columbus Ohio, 43221, United States
Cancer Therapy & Research Center @ UTHSCSA
San Antonio Texas, 78229, United States
Seattle Cancer Care Alliance
Seattle Washington, 98109, United States
University of Washington Medical Center
Seattle Washington, 98195, United States
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How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Phase:

Phase 1

Estimated Enrollment:

27

Study ID:

NCT00965731

Recruitment Status:

Completed

Sponsor:


Pfizer

How clear is this clinincal trial information?

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