Lung Cancer Clinical Trial

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Molecular Markers in Predicting Lung Cancer Development Using Tissue Samples From Healthy Participants

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Summary

RATIONALE: Studying samples of blood, urine, sputum, mouth cells, and bronchial tissue from healthy participants in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors learn more about the development of cancer.

PURPOSE: This laboratory study is looking for molecular markers in predicting lung cancer development using tissue samples from healthy participants.

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Full Description

OBJECTIVES:

To obtain biological specimens from healthy participants with no known risk of lung cancer to use as controls in the study of lung cancer progression.
To identify new molecular abnormalities specific to the development of squamous cell carcinoma of the lung.

OUTLINE: Serum, urine, sputum, and buccal cell samples are collected. Patients also undergo bronchoscopy for collection of bronchial tissue and bronchial brush samples. The samples are used for genomic and proteomic studies to identify new molecular abnormalities specific to the development of lung cancer.

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Eligibility Criteria

DISEASE CHARACTERISTICS:

Healthy participant

No history of smoking
No history of cancer

PATIENT CHARACTERISTICS:

SWOG performance status 0
No clinically apparent bleeding diathesis

PRIOR CONCURRENT THERAPY:

Not specified

Study is for people with:

Lung Cancer

Estimated Enrollment:

37

Study ID:

NCT00899457

Recruitment Status:

Completed

Sponsor:

Vanderbilt-Ingram Cancer Center

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There are 2 Locations for this study

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Vanderbilt-Ingram Cancer Center - Cool Springs
Nashville Tennessee, 37064, United States
Vanderbilt-Ingram Cancer Center at Franklin
Nashville Tennessee, 37064, United States
Vanderbilt-Ingram Cancer Center
Nashville Tennessee, 37232, United States

How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Estimated Enrollment:

37

Study ID:

NCT00899457

Recruitment Status:

Completed

Sponsor:


Vanderbilt-Ingram Cancer Center

How clear is this clinincal trial information?

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