Lung Cancer Clinical Trial
Pilot Study of Model Based Iterative Reconstruction Using 64-Slice
Summary
This study is being performed to confirm that the new technique, Model-Based Iterative Reconstruction (MBIR) with reduced radiation dose can deliver equivalent image quality for CT scans compared to current techniques (Filtered Back Projection with Adaptive Statistical Iterative Reconstruction (FBP with ASiR) and also to demonstrate that MBIR can improve general image quality characteristics at equivalent radiation dose levels.
Full Description
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Eligibility Criteria
Inclusion Criteria:
Men or Women 30 years of age or older voluntarily willing to sign an informed consent.
Patients indicated for one of the following:
CNS: Known or suspected pathology in the posterior fossa Thorax: Patients referred for staging of a known or suspected lung cancer Abdomen: Patients with acute flank pain and suspected urolithiasis or Abdomen: Patients with a known or suspected focal liver lesion
Exclusion Criteria:
Subjects less than 30 years of age
Pregnant women as confirmed by urine test or current accepted institution standard
If IV contrast is required:
Severe or uncontrolled allergy to iodinated contrast media
Serum creatinine > 1.7 mg/dl or estimated glomerular filtration rate [eGFR] of <60 mg/min as recorded in medical file or by current accepted institution standard
Unable or unwilling to provide written informed consent by self or legal guardian at the time of study enrollment
Unstable physical condition as identified by physician
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There are 3 Locations for this study
Boston Massachusetts, 02114, United States
Durham North Carolina, 27710, United States
Miwaukee Wisconsin, 53226, United States
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