Proton Radiation Therapy With Cisplatin and Etoposide Followed by Surgery in Stage III Non-Small Cell Lung Cancer

Inclusion Criteria:

Histologically confirmed non-small cell lung cancer with a clinical stage of IIIA
Candidate for chemoradiation and surgical resection
Measurable disease
Life expectancy > 6 months
Normal organ and marrow function

Exclusion Criteria:

Pregnant or breast-feeding
Prior therapy for lung cancer with chemotherapy
Prior chest radiation
Compromised pulmonary function
Severe neurovascular disease
History of high cardiac risk including unstable angina
History of allergic reactions attributed to compounds of similar chemical or biologic composition to cisplatin or etoposide
Uncontrolled intercurrent illness including, but not limited to ongoing or active infection, symptomatic congestive hear failure, unstable angina pectoris, clinically significant or serious cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
History of a different malignancy unless disease-free for at least 3 years and at low risk for recurrence. Individuals with the following cancers are eligible if diagnosed and treated within the past 3 years: cervical cancer in situ, non muscle-invasive bladder cancer, basal cell or squamous cell carcinoma of the skin
Subjects with HIV