Lung Cancer Clinical Trial

Study to Compare Furmonertinib to Platinum-Based Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations (FURVENT)

Summary

Global, Phase 3, randomized, multicenter, open-label study evaluating the efficacy and safety of furmonertinib at 2 dose levels (160 mg once daily [QD] and 240 mg QD) compared to platinum-based chemotherapy in previously untreated patients with locally advanced or metastatic non-squamous Non-Small Cell Lung Cancer (NSCLC) with Epidermal Growth Factor Receptor (EGFR) exon 20 insertion mutations. A target of approximately 375 patients will be randomized in a 1:1:1 ratio to treatment with furmonertinib 240 mg QD, furmonertinib 160 mg QD, or platinum-based chemotherapy.

View Eligibility Criteria

Eligibility Criteria

Key Inclusion Criteria:

Histologically or cytologically documented, locally advanced or metastatic non-squamous Non-Small Cell Lung Cancer (NSCLC) not amenable to curative surgery or radiotherapy.
Documented results of the presence of an Epidermal Growth Factor Receptor (EGFR) exon 20 insertion mutation in tumor tissue or blood from local or central testing.
No prior systemic anticancer therapy regimens received for locally advanced or metastatic Non-Small Cell Lung Cancer (NSCLC) including prior treatment with any Epidermal Growth Factor Receptor (EGFR)-targeting agents (e.g., previous (EGFR) TKIs, monoclonal antibodies, or bispecific antibodies).
Patients who have received prior neo-adjuvant and/or adjuvant chemotherapy, immunotherapy, or chemo radiotherapy for non-metastatic disease (excluding EGFR-TKIs) must have experienced a treatment free interval of at least 12 months.
Patients with a history of treated CNS metastases or new asymptomatic CNS metastases are eligible.

Study is for people with:

Lung Cancer

Phase:

Phase 3

Estimated Enrollment:

375

Study ID:

NCT05607550

Recruitment Status:

Recruiting

Sponsor:

ArriVent BioPharma, Inc.

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There are 195 Locations for this study

See Locations Near You

Arrivent Investigative Site
Daphne Alabama, 36526, United States More Info
Arrivent Investigative Site
Yuma Arizona, 85364, United States
Arrivent Investigative Site
Fayetteville Arkansas, 72703, United States
Arrivent Investigative Site
Beverly Hills California, 90212, United States
Arrivent Investigative Site
Fullerton California, 92835, United States
Arrivent Investigative Site
Long Beach California, 90806, United States
Arrivent Investigative Site
Los Alamitos California, 90720, United States
Arrivent Investigative Site
Napa California, 94558, United States
Arrivent Investigative Site
Orange California, 90868, United States
Arrivent Investigative Site
Orange California, 92868, United States
Arrivent Investigative site
Sacramento California, 95817, United States More Info
Arrivent Investigative Site
San Diego California, 92123, United States
Arrivent Investigative Site
Santa Barbara California, 93105, United States
Arrivent Investigative Site
Santa Monica California, 90404, United States More Info
Arrivent Investigative Site
Santa Rosa California, 95403, United States
Arrivent Investigative Site
Whittier California, 90602, United States
Arrivent Investigative Site
Hartford Connecticut, 06102, United States
Arrivent Investigative Site
Norwich Connecticut, 06360, United States
Arrivent Investigative Site
Fort Myers Florida, 33901, United States More Info
Arrivent Investigative Site
Saint Petersburg Florida, 33705, United States More Info
Arrivent Investigative Site
The Villages Florida, 32159, United States
Arrivent Investigative Site
Peoria Illinois, 61615, United States
Arrivent Investigative Site
Rolling Meadows Illinois, 60008, United States
Arrivent Investigative Site
Fort Wayne Indiana, 46804, United States
Arrivent Investigative Site
Indianapolis Indiana, 46250, United States
Arrivent Investigative Site
South Bend Indiana, 46601, United States
Arrivent Investigative Site
Bethesda Maryland, 20817, United States More Info
Arrivent Investigative Site
Frederick Maryland, 21702, United States
Arrivent Investigative Site
Rockville Maryland, 20850, United States
Arrivent Investigative Site
Fairhaven Massachusetts, 02719, United States
Arrivent Investigative Site
Lansing Michigan, 48912, United States
Arrivent Investigative Site
Bolivar Missouri, 65613, United States
Arrivent Investigative Site
Kansas City Missouri, 64111, United States
Arrivent Investigative Site
Saint Joseph Missouri, 64507, United States
Arrivent Investigative Site
Saint Louis Missouri, 63110, United States
Arrivent Investigative Site
Omaha Nebraska, 68114, United States More Info
Arrivent Investigative Site
Belleville New Jersey, 07109, United States
Arrivent Investigative Site
Englewood New Jersey, 07631, United States
Arrivent Investigative Site
Florham Park New Jersey, 07932, United States
Arrivent Investigative Site
Bronx New York, 10461, United States More Info
Arrivent Investigative Site
Goldsboro North Carolina, 27534, United States
ArriVent Investigative Site
Pinehurst North Carolina, 28374, United States More Info
Arrivent Investigative Site
Canton Ohio, 44708, United States
Arrivent Investigative Site
Cincinnati Ohio, 45220, United States
ArriVent Investigative Site
Cincinnati Ohio, 45242, United States More Info
Arrivent Investigative Site
Cleveland Ohio, 44195, United States
Arrivent Investigative Site
Columbus Ohio, 43214, United States
Arrivent Investigative Site
Oklahoma City Oklahoma, 73102, United States
Arrivent Investigative Site
Tulsa Oklahoma, 74146, United States
Arrivent Investigative Site
Salem Oregon, 97301, United States More Info
Arrivent Investigative Site
Gettysburg Pennsylvania, 17325, United States
ArriVent Investigative Site
Langhorne Pennsylvania, 19047, United States More Info
ArriVent I Site
Contact
[email protected]
Arrivent Investigative Site
York Pennsylvania, 17403, United States
Arrivent Investigative Site
Greenville South Carolina, 29607, United States
Arrivent Investigative Site
Sioux Falls South Dakota, 57117, United States
Arrivent Investigative Site
Memphis Tennessee, 38120, United States
ArriVent Investigative Site
Nashville Tennessee, 37203, United States More Info
Arrivent Investigative Site
Abilene Texas, 79606, United States More Info
ArriVent Investigative Site
Austin Texas, 78745, United States More Info
Arrivent Investigative Site
Houston Texas, 77030, United States
Arrivent Investigative Site
Plano Texas, 75093, United States More Info
Arrivent Investigative Site
Ogden Utah, 84405, United States
Arrivent Investigative Site
Salt Lake City Utah, 84106, United States
ArriVent Investigative Site
Fairfax Virginia, 22031, United States More Info
Arrivent Investigative Site
Fredericksburg Virginia, 22408, United States
Arrivent Investigative Site
Bellingham Washington, 98225, United States
Arrivent Investigative Site
Spokane Valley Washington, 99216, United States
Arrivent Investigative Site
Tacoma Washington, 98405, United States
Arrivent Investigative Site
Appleton Wisconsin, 54911, United States
ArriVent Investigative Site
Heidelberg Victoria, 3084, Australia More Info
Arrivent Investigative Site
Blacktown , 2148, Australia More Info
Arrivent Investigative Site
St Leonards , NSW 2, Australia More Info
Arrivent Investigative Site
Woolloongabba , 4102, Australia More Info
ArriVent Investigative Site
Salvador Bahia, 40170, Brazil More Info
ArriVent Investigative Site
Belo Horizonte Minas Gerais, 30130, Brazil More Info
ArriVent Investigative Site
Porto Alegre Rio Grande, 90035, Brazil More Info
ArriVent Investigative Site
Rio De Janeiro RJ, 20231, Brazil More Info
ArriVent Investigative Site
Rio De Janeiro RJ, 22281, Brazil More Info
ArriVent
Contact
[email protected]
ArriVent Investigative Site
Pelotas RS, 96020, Brazil More Info
ArriVent Investigative Site
São José Do Rio Preto Sao Paulo, 15090, Brazil More Info
ArriVent Investigative Site
São Paulo Sao Paulo, 01321, Brazil More Info
ArriVent Investigative Site
Blumenau SC Cep, 89015, Brazil More Info
ArriVent Investigative Site
Liberdade São Paulo/SP, 01509, Brazil More Info
ArriVent Investigative Site
Taubaté Taubate SP, 12030, Brazil More Info
ArriVent Investigative Site
Porto Alegre , 91350, Brazil More Info
ArriVent Investigative Site
Beijing Beijing, 10114, China
Allist Investigative Site
Xuhui Hai City, 20003, China More Info
Allist Investigative Site
Hangzhou Hangzhou, 31001, China More Info
Allist I Site
Contact
[email protected]
Allist Investigative Site
Cangzhou Hebei, 06101, China More Info
Allist I Site
Contact
[email protected]
Allist Investigative Site
Shushan Hefei, 23002, China More Info
Allist Investigative Site
Zhengzhou Henan, 45005, China More Info
Allist Investigative Site
Changchun Jilin, 13000, China More Info
Allist Investigative Site
Weihai Lingang Economic And Technological Development Zo, 26420, China More Info
Allist Investigative Site
Meijiang Meizhou City, Guangdong Province, 51400, China More Info
Allist Investigative Site
Yangpu Shanghai, 20043, China More Info
Allist I Site
Contact
[email protected]
Allist Investigative Site
Taiyuan Taiyuan, 03001, China More Info
Allist I Site
Contact
[email protected]
Allist Investigative Site
Anyang , 45500, China More Info
Allist Investigative Site
Changchun , 13000, China More Info
Allist Investigative Site
Changsha , 41000, China More Info
Allist Investigative Site
Changsha , 41003, China More Info
Allist Investigative Site
Chengdu , 61004, China More Info
Allist Investigative Site
Chenzhou , 42309, China More Info
Allist Investigative Site
Chongqing , 40003, China More Info
Allist Investigative Site
Guangzhou , 51006, China More Info
Site 156044
Contact
[email protected]
Allist Investigative Site
Guangzhou , 51028, China More Info
Allist Investigative Site
Harbin , 15008, China More Info
Allist Investigative Site
Hefei , 23008, China More Info
Allist Investigative Site
Huai'an , 22330, China More Info
Allist Investigative Site
Huizhou , 51600, China More Info
Allist Investigative Site
Jinan , 25001, China More Info
Allist Investigative Site
Jinan , 25011, China More Info
Allist Investigative Site
Jining , 27200, China More Info
Allist Investigative Site
Lanzhou , 73003, China More Info
Allist Investigative Site
Lishui , 32302, China More Info
Allist Investigative Site
Luoyang , 47100, China More Info
Allist Investigative Site
Nanchang , 33000, China More Info
Allist Investigative Site
Nanchang , 33004, China More Info
Allist Investigative Site
Nanjing , 21000, China More Info
Allist Investigative Site
Ningbo , 31504, China More Info
Allist Investigative Site
Shanghai , 20043, China More Info
Allist Investigative Site
Shantou , 51503, China More Info
Allist Investigative Site
Shenyang , 11004, China More Info
Allist Investigative Site
Shenzhen , 51800, China More Info
Allist Investigative Site
Taiyuan , 03000, China More Info
Allist Investigative Site
Taoyuan , 30000, China More Info
Allist Investigative Site
Tianjin , 30006, China More Info
Allist Investigative Site
Weihui , 45300, China More Info
Allist Investigative Site
Wuhan , 43002, China More Info
Allist Investigative Site
Xiamen , 36100, China More Info
Allist Investigative Site
Xianyang , 44113, China More Info
Allist Investigative Site
Xinxiang , 45300, China More Info
Allist Investigative Site
Xuzhou , 22100, China More Info
Allist Investigative Site
Zhengzhou , 45000, China More Info
Arrivent Investigative Site
Caen , 14000, France More Info
Arrivent Investigative Site
Lyon , 69003, France More Info
Arrivent Investigative Site
Lyon , 69008, France More Info
Arrivent Investigative Site
Marseille , 13915, France More Info
Arrivent Investigative Site
Toulouse , 31059, France More Info
Arrivent Investigative Site
Villejuif , 94800, France More Info
ArriVent Investigative Site
Be'er Sheva , 84101, Israel More Info
ArriVent Site
Contact
[email protected]
ArriVent Investigative Site
Haifa , 31096, Israel More Info
ArriVent Investigative Site
Jerusalem , 91031, Israel More Info
ArriVent Investigative Site
Rozzano Milan, 20089, Italy More Info
ArriVent Investigative Site
Roma Rome, 00144, Italy More Info
ArriVent Investigative Site
Bari , 70124, Italy More Info
Arrivent Investigative Site
Meldola , 47014, Italy More Info
ArriVent Investigative Site
Milano , 20141, Italy More Info
ArriVent
Contact
[email protected]
ArriVent Investigative Site
Kurume Fukuoka, 830-0, Japan More Info
Arrivent Investigative Site
Akashi , 673-8, Japan More Info
Arrivent Investigative Site
Hirakata , 573-1, Japan More Info
Arrivent Investigative Site
Kashiwa , 277-8, Japan More Info
Arrivent Investigative Site
Nagoya , 460-0, Japan More Info
Arrivent Investigative Site
Sapporo-shi , 003-0, Japan More Info
Arrivent Investigative Site
Sendai , 980-0, Japan More Info
Arrivent Investigative Site
Shizuoka , 41187, Japan More Info
Arrivent Investigative Site
Tokyo , 113-8, Japan More Info
Arrivent Investigative Site
Ube , 755-0, Japan More Info
Arrivent Investigative Site
Yokohama , 241-8, Japan More Info
Arrivent Investigative Site
Ōsaka-sayama , 589-8, Japan More Info
ArriVent Investigative Site
Jungni I Gu Seoul, 03181, Korea, Republic of More Info
Arrivent Investigative Site
Busan , 49241, Korea, Republic of More Info
Arrivent Investigative Site
Hwasun , 58128, Korea, Republic of More Info
Arrivent Investigative Site
Seoul , 2447, Korea, Republic of More Info
Arrivent Investigative Site
Seoul , 3722, Korea, Republic of More Info
Arrivent Investigative Site
Seoul , 5505, Korea, Republic of More Info
Arrivent Investigative Site
Seoul , 6351, Korea, Republic of More Info
ArriVent Investigative Site
George Town Pulau Pinang, 10990, Malaysia More Info
Arrivent Investigative Site
Cheras , 56000, Malaysia More Info
Arrivent Investigative Site
Kota Bharu , 15586, Malaysia More Info
Arrivent Investigative Site
Kuala Lumpur , 50586, Malaysia More Info
Arrivent Investigative Site
Kuching , 93586, Malaysia More Info
Arrivent Investigative Site
Amsterdam , 1066 , Netherlands More Info
Arrivent Investigative Site
Harderwijk , 3844D, Netherlands More Info
Arrivent Investigative Site
Cebu , 6000, Philippines More Info
Arrivent Investigative Site
Davao City , 8000, Philippines More Info
ArriVent Investigative Site
Manila , 1000, Philippines More Info
Arrivent Investigative Site
Pasig , 1600, Philippines More Info
ArriVent Investigative Site
Singapore , 11907, Singapore More Info
Arrivent Investigative Site
Singapore , 16961, Singapore More Info
ArriVent Investigative Site
Málaga Malaga, 29011, Spain More Info
Arrivent Investigative Site
A Coruña , 15006, Spain More Info
Arrivent Investigative Site
Barcelona , 08035, Spain More Info
ArriVent Investigative Site
Madrid , 28020, Spain More Info
ArriVent Site
Contact
[email protected]
Arrivent Investigative Site
Valencia , 46026, Spain More Info
Arrivent Investigative Site
Chang Hua , 50006, Taiwan More Info
Arrivent Investigative Site
Kaohsiung , 807, Taiwan More Info
ArriVent Investigative Site
Kaohsiung , 82445, Taiwan More Info
ArriVent Site
Contact
[email protected]
ArriVent Investigative Site
Taichung , 40721, Taiwan More Info
Arrivent Investigative Site
Tainan , 704, Taiwan More Info
Arrivent Investigative Site
Taipei , 10048, Taiwan More Info
Arrivent Investigative Site
Bangkok , 10210, Thailand More Info
Arrivent Investigative Site
Bangkok , 10330, Thailand More Info
Arrivent Investigative Site
Bangkok , 10400, Thailand More Info
Arrivent Investigative Site
Hat Yai , 90110, Thailand More Info
ArriVent Investigative Site
Guildford Surrey, GU2 7, United Kingdom More Info
ArriVent Site
Contact
[email protected]
ArriVent Investigative Site
London , SW3 6, United Kingdom More Info
ArriVent I Site
Contact
[email protected]
ArriVent Investigative Site
Manchester , M20 4, United Kingdom More Info
ArriVent
Contact
[email protected]
ArriVent Investigative Site
Sutton , SM2 5, United Kingdom More Info
ArriVent I Site
Contact
[email protected]

How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Phase:

Phase 3

Estimated Enrollment:

375

Study ID:

NCT05607550

Recruitment Status:

Recruiting

Sponsor:


ArriVent BioPharma, Inc.

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.