Melanoma Clinical Trial

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Study Evaluating Single and Repeated Intravitreal Doses of ICON-1 in Patients With Uveal Melanoma

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Summary

The purpose of this study is to evaluate the safety, tolerability, biological activity, pharmacokinetics and pharmacodynamic activity of single and repeated escalating intravitreal doses of ICON-1 in patients with primary uveal melanoma who are planned to undergo enucleation or brachytherapy of the affected eye.

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Eligibility Criteria

Inclusion Criteria:

Males or females of any race at least 18 years of age
Clinical diagnosis of primary uveal melanoma involving the posterior uveal tract in the study eye
Planned enucleation or brachytherapy of the study eye due to uveal melanoma

Exclusion Criteria:

Uveal melanoma in the study eye originating in the anterior uveal tract (iris)
Hereditary or chronic hemorrhagic or coagulopathy conditions (i.e., hemophilia)
Woman who is pregnant or lactating

Study is for people with:

Melanoma

Phase:

Phase 1

Estimated Enrollment:

10

Study ID:

NCT02771340

Recruitment Status:

Completed

Sponsor:

Iconic Therapeutics, Inc.

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There are 8 Locations for this study

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San Francisco California, 94109, United States

Denver Colorado, 80401, United States

Leawood Kansas, 66211, United States

Boston Massachusetts, 02114, United States

Grand Rapids Michigan, 49546, United States

Royal Oak Michigan, 48073, United States

Portland Oregon, 97239, United States

Philadelphia Pennsylvania, 19107, United States
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How clear is this clinincal trial information?

Study is for people with:

Melanoma

Phase:

Phase 1

Estimated Enrollment:

10

Study ID:

NCT02771340

Recruitment Status:

Completed

Sponsor:


Iconic Therapeutics, Inc.

How clear is this clinincal trial information?

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