Multiple Myeloma Clinical Trial

A Phase I Open Label Study of the Safety and Tolerability of Elotuzumab (BMS-901608) Administered in Combination With Either Lirilumab (BMS-986015) or Urelumab (BMS-663513) in Subjects With Multiple Myeloma

Summary

To assess the safety and tolerability, characterize the dose limiting toxicities (DLTs) and identify the maximally tolerated dose (MTD) of Elotuzumab administered in combination with either Lirilumab or Urelumab in subjects with multiple myeloma.

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Full Description

Allocation:

Part1: Non-randomized
Part2: Randomized

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Eligibility Criteria

For more information regarding BMS clinical trial participation, please visit www.BMSStudyConnect.com

Inclusion Criteria:

Subjects must have histological confirmation of multiple myeloma with measurable disease (per International Myeloma Working Group (IMWG) criteria):

Relapsed/refractory multiple myeloma, subjects who are post autologous transplant and have achieved very good partial response (VGPR) or complete response (nCR) with minimal residual disease (MRD)

Study is for people with:

Multiple Myeloma

Phase:

Phase 1

Estimated Enrollment:

44

Study ID:

NCT02252263

Recruitment Status:

Completed

Sponsor:

Bristol-Myers Squibb

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There are 6 Locations for this study

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University Of Arkansas For Medical Sciences
Little Rock Arkansas, , United States
The Sidney Kimmel Comprehensive Cancer Center
Baltimore Maryland, 21287, United States
Memorial Sloan Kettering Cancer Center
New York New York, 10065, United States
The Ohio State University
Columbus Ohio, 43210, United States
Oregon Health & Science University
Portland Oregon, 97239, United States
University Of Pennsylvania
Philadelphia Pennsylvania, 19104, United States
Local Institution
Pamplona Navarra, 31008, Spain

How clear is this clinincal trial information?

Study is for people with:

Multiple Myeloma

Phase:

Phase 1

Estimated Enrollment:

44

Study ID:

NCT02252263

Recruitment Status:

Completed

Sponsor:


Bristol-Myers Squibb

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