Multiple Myeloma Clinical Trial

Determining Normal Range for Free Light Chains in Serum Among Twins

Summary

The objective of this study is to recruit healthy adult identical and fraternal twins for the collection of one teaspoon of blood to be sent to the Clinical Lab at San Francisco General Hospital. The serum will be tested to determine the reference range for free light chains.

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Full Description

Serum free light chains are used to assist in the diagnosis of multiple myeloma. The test measures kappa (K) and lambda (L) chains, and the calculation of the ratio of kappa to lambda (K/L). Previous studies have shown that the K/L ratio does not change over time (1 year). The hypothesis of this study is that healthy twins will have a K/L ratio that are close to each other in value, suggesting that this ratio is genetically linked.

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Eligibility Criteria

Inclusion Criteria:

Healthy subjects 18-80 years.
Must be an identical or fraternal twin (both must be recruited)

Exclusion Criteria:

Symptoms suggestive of multiple myeloma (e.g., renal insufficiency, anemia, bone pain) -

Study is for people with:

Multiple Myeloma

Estimated Enrollment:

100

Study ID:

NCT04191057

Recruitment Status:

Recruiting

Sponsor:

University of California, San Francisco

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There is 1 Location for this study

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San Francisco General Hospital
San Francisco California, 94306, United States More Info
Alan Wu, Ph.D.
Contact
628-206-3540
[email protected]

How clear is this clinincal trial information?

Study is for people with:

Multiple Myeloma

Estimated Enrollment:

100

Study ID:

NCT04191057

Recruitment Status:

Recruiting

Sponsor:


University of California, San Francisco

How clear is this clinincal trial information?

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