Multiple Myeloma Clinical Trial
The TOTOM Trial: Tai Chi to Optimize Transplant Outcomes for Multiple Myeloma
The current proposal aims to test the feasibility of immune function analysis for Tai Chi Easy (TCE) intervention in multiple myeloma (MM) patients undergoing autologous stem cell transplantation (ASCT) with concurrent exploration of health related quality of life (HRQOL).
The current proposal aims to test the feasibility of immune function analysis for TCE intervention in MM patients undergoing ASCT with concurrent exploration of HRQOL. The data obtained from this trial will provide supporting data for a future randomized clinical trial evaluating the impact of TCE on immune function (incidence of ASCT related infectious complications, natural killer cell phenotype and activity, and myeloma remission rate (clonal plasma cell % at day 100, minimal residual disease (MRD)), with the evaluation of efficacy on improving HRQOL during ASCT. Successful completion of this CROC project will provide necessary data to support future grant applications, in particular the feasibility of immunoassay evaluation of MM patients undergoing ASCT.
Diagnosis of Multiple Myeloma planned to undergo bone marrow transplant
18 years or older
General proficiency to read/write in English
Able to attend TCE training session per study protocol
ECOG performance status 0-1
Currently performs Tai Chi, QiQong, or Yoga at least once weekly or more
Syncopal event in prior 60 days
Concurrent major depressive disorder or anxiety disorder (DSMIV)
Chronic dizziness or vestibular disorders
History of recurrent falls (>2 in the prior year)
Grade 3 or greater neuropathy
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There is 1 Location for this study
Tucson Arizona, 85724, United States More Info
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