Multiple Myeloma Clinical Trial

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Zoledronic Acid Treatment (Every 4 or 12 Weeks) to Prevent Skeletal Complications in Advanced Multiple Myeloma Participants

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Summary

This study evaluated the effectiveness and safety of a dosing method for zoledronic acid in preventing skeletal complications in multiple myeloma participants who have been on an intravenous (IV) bisphosphonate for about one to two years.

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Eligibility Criteria

Inclusion Criteria:

Confirmed diagnosis of multiple myeloma
Have been on zoledronic acid or pamidronate for 1-2 years and therapy must have been initiated for osteolytic lesion, bone fracture, spinal compression, or osteopenia due to multiple myeloma
Stable renal function

Exclusion Criteria:

Known sensitivity to bisphosphonates
Receiving investigational drugs considered not safe for co-administration or have a significant effect on bone turnover
Current active dental problems
Had bone marrow transplant or blood stem cell transplant within 2 months before study entry or planned transplant within 2 months following enrollment

Other protocol-defined inclusion/exclusion criteria may apply.

Study is for people with:

Multiple Myeloma

Phase:

Phase 4

Estimated Enrollment:

121

Study ID:

NCT00622505

Recruitment Status:

Completed

Sponsor:

Novartis Pharmaceuticals

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There are 41 Locations for this study

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TriValley Cancer Research and Treatment Center
Casa Grande Arizona, 85222, United States
Wilshire Oncology Medical Group
La Verne California, 91750, United States
Cedars Sinai Medical Center Outpatient Cancer Ctr. (4)
Los Angeles California, 90048, United States
Palo Alto Medical Foundation Hematology/Oncology
Mountain View California, 94040, United States
Oncology Care Medical Associates
San Gabriel California, 91776, United States
Santa Clara Valley Health & Hospital System
San Jose California, 95128, United States
University of Colorado U of Colorado Cancer Center
Aurora Colorado, 80045, United States
Hematology Oncology PC
Stamford Connecticut, 06902, United States
Washington Hospital Center
Washington District of Columbia, 20010, United States
Palm Beach Institute of Hematology Oncology
Boynton Beach Florida, 33435, United States
Innovative Medical Research of South Florida Innovative Med Research
Miami Shores Florida, 33138, United States
Cancer Centers of Florida PA Cancer Centers of Central FL
Ocoee Florida, *see , United States
Integrated Community Oncology Network Florida Oncology Associates
Orange Park Florida, 32073, United States
Cleveland Clinic Florida
Weston Florida, 33331, United States
Loyola University Medical Center /Cardinal Bernardin Cancer Loyola Univ Med Ctr
Maywood Illinois, 60153, United States
University of Maryland Greenebaum Cancer Center
Baltimore Maryland, 21201, United States
Center for Cancer & Blood Disorders
Bethesda Maryland, 20817, United States
Oncology - Hematology Associates, PA Oncology Hematology Assoc
Clinton Maryland, 20735, United States
Dana Farber Cancer Institute Clinical Research Coordinator
Boston Massachusetts, 02115, United States
Boston VA Healthcare Boston VA
Boston Massachusetts, 02131, United States
Berkshire Hematology Oncology
Pittsfield Massachusetts, 01201, United States
N MS Hematology & Oncology
Tupelo Mississippi, 38801, United States
Hematology & Oncology Consultants, PC Hematology & Oncology
Omaha Nebraska, 68122, United States
Somerset Hematology Oncology Associates Somerset Hema Oncol Assoc (2)
Somerset New Jersey, 08873, United States
Cooper Cancer Center
Voorhees New Jersey, 08043, United States
Rochester General Hospital / Lipson Cancer Center Lipson Cancer Center
Rochester New York, 14621, United States
University of Rochester MC / James P. Wilmot Cancer Center James P. Wilmot Cancer Center
Rochester New York, 14642, United States
SUNY - Upstate Medical University Div. of Hematology-Oncology
Syracuse New York, 13210, United States
Carolina Oncology Specialists, PC
Hickory North Carolina, 28602, United States
Regional Hematology-Oncology Associates PC
Langhorne Pennsylvania, 19047, United States
Temple University Temple University
Philadelphia Pennsylvania, 19140, United States
Medical Associates, PA
Charleston South Carolina, 29403, United States
Low Country Hematology Oncology Dept of Lowcountry Hem/Onc
Mount Pleasant South Carolina, 29464, United States
Lexington Oncology Associates
West Columbia South Carolina, 29169, United States
Avera Research Institute
Sioux Falls South Dakota, 57105, United States
Blood and Cancer Center of East Texas
Tyler Texas, 75701, United States
East Texas Medical Center Cancer Institute
Tyler Texas, 75701, United States
Northern Utah Cancer Associates Dept.ofNorthernUtahAssoc.
Ogden Utah, 84403, United States
Central Utah Clinic Central Utah Clinic (8)
Provo Utah, 84604, United States
Peninsula Cancer Institute
Newport News Virginia, 23601, United States
Swedish Cancer Institute
Seattle Washington, 98104, United States
West Virginia University Health Research Center Clinical Trial Research Unit
Morgantown West Virginia, 26506, United States
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How clear is this clinincal trial information?

Study is for people with:

Multiple Myeloma

Phase:

Phase 4

Estimated Enrollment:

121

Study ID:

NCT00622505

Recruitment Status:

Completed

Sponsor:


Novartis Pharmaceuticals

How clear is this clinincal trial information?

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