Multiple Sclerosis Clinical Trial
Evaluation of Coagulation in Multiple Sclerosis
Summary
Recent research in multiple sclerosis (MS) have suggested that altered coagulation and vascular inflammation may play a role in pathophysiology of MS. Sonoclot is viscoelastic method of analyzing clot formation. This instrument will be used to compare coagulation in individuals with MS to healthy controls. A 24-hour dietary recall and food frequency questionnaire will help determine whether coagulation is modified by fish consumption.
Full Description
This case-control study will recruit individuals with a diagnosis of MS and healthy controls. Individuals will be asked to come to Bastyr Clinical Research Center for a single study visit, at which time dietary intake, current medications and supplements, other medical diagnoses, and coagulation will be evaluated.
Eligibility Criteria
Inclusion Criteria:
Diagnosis of clinically probable of clinically definite multiple sclerosis made by board certified neurologist. Subject must be willing to release medical information regarding diagnosis
Controls must consider themselves healthy and be free of any neurological, autoimmune, endocrine or other chronic disease. Must also be free of any recent acute illness/injury that can influence inflammatory activity.
Individuals must be 18 or older
Exclusion Criteria:
Diagnosis of coagulation defect
Use of anticoagulants (eg. warfarin, coumadin) or Aspirin within 30 days of entry.
NSAID within 7 days of entry (dietary intake of fish oil or tumeric is acceptable)
Pregnancy
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There is 1 Location for this study
Kenmore Washington, 98028, United States
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