Multiple Sclerosis Clinical Trial
Exploratory Study on the Timing of Multiple Sclerosis (MS) Symptoms
The investigators' overall hypothesis is that appearance or worsening of relapsing-remitting multiple sclerosis (RR-MS) symptoms are affected by various factors including stress, hormonal cycles, illness and missed medications.
Fluctuations in MS symptoms in women with RR-MS might be affected by a variety of factors. To determine which factors are important, we are asking subjects to fill out a diary and calendar on a daily basis for 90 days. After an initial instructional meeting over the phone, the materials are filled out at home and returned monthly via postage-paid envelopes provided by the study. Compensation ($10 gift card) is sent after each monthly diary is received. The diary includes a list of symptoms and a rank scale for the women to show subtle changes in MS symptoms. The calendar allows the subject to denote additional factors such as stress, hormonal cycles, illnesses or immunizations and changed or missed medications. We anticipate that statistical analysis will reveal which of these factors affect women with relapsing-remitting multiple sclerosis.
diagnosed with relapsing-remitting multiple sclerosis
no diagnosis of relapsing-remitting MS
diagnosis of any other autoimmune disease or fibromyalgia
peri-, post-, or surgically menopausal
pregnant within past year or nursing
history of chemotherapy
on experimental medications
treatment with steroids in the last 30 days
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