Multiple Sclerosis Clinical Trial
LSFG-SKIN, Laser Speckle Flowgraphy
Summary
The purpose of this project is to quantify normal and abnormal skin blood flow regionally in different areas of the body(face, extremities, over burns and wounds) at baseline and over time in response to treatment or environmental changes, such as temperature, light and pressure.
Full Description
Laser speckle skin blood flow (LSFG-SKIN) will be recorded in normal subjects and in patients with disorders affecting skin capillary perfusion, which may include cardiovascular disorders, dermatologic disorders, skin wounds, ocular disorders, psychiatric disorders, and neurologic disorders.
Eligibility Criteria
Inclusion Criteria:
Controls
â—Healthy normal control subjects ages 18-90
Cardiology Subjects
Ages 18-90
History of dysrhythmia, heart failure, cardiac ischemia, hypertension, peripheral vascular disease
Dermatology Subjects
Ages 18-90
History of inflammatory and cancerous lesions
Endocrine Subjects
Ages 18-90
History of diabetes, thyroid disease
Neurology Subjects
Ages 18-90
History of dementia, headaches, Parkinson's, light sensitivity, stroke, TIA, multiple sclerosis
Psychiatry Subjects
Ages 18-90
History of bipolar, schizophrenia, anxiety, depression
Surgery Subjects
Ages 18-90
History of skin wounds(trauma, chemotherapy, radiation), thermal burns, or plastic and reconstructive surgical procedures.
Ophthalmology Subjects
Ages 18-90
History of ocular disorders caused by hypo perfusion or inflammatory disorders
Exclusion Criteria:
Controls
Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
Angle closure glaucoma
Cardiology Subjects
Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
Angle closure glaucoma
3. Dermatology Subjects
Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
Angle closure glaucoma
Endocrine Subjects
Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
Angle closure glaucoma
Neurology Subjects
Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
Angle closure glaucoma
Psychiatry Subjects
Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
Angle closure glaucoma
Surgery Subjects
Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
Angle closure glaucoma
Ophthalmology Subjects
Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
Angle closure glaucoma
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There is 1 Location for this study
Iowa City Iowa, 52242, United States
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