Multiple Sclerosis Clinical Trial
Management of Pain in Persons With Multiple Sclerosis
Summary
The purpose of this study is to see if treatments that include components of self-hypnosis training and cognitive behavioral therapy (CBT) can help decrease pain in people with MS.
Full Description
This study examined the benefits of two treatments, individually and together, for helping individuals with MS manage their pain. We conducted a time series design in which MS subjects received all four treatment conditions in two orders (randomly assigned): (1) Control (education intervention-CONT),Self-Hypnosis Training (HYP), Cognitive Behavioral Therapy (CBT), HYP-CBT(a combination of HYP and CBT) and (2) CONT, CBT, HYP, HYP-CBT. Subjects attended 16 60-minute treatment sessions conducted by one of the study's psychologists either at the UW,HMC or in the subject's home. Each subject received four treatment sessions of each treatment module listed above. Primary outcome measures were collected via the telephone and mail by research personnel blind to the treatment condition before treatment, immediately after treatment ends and one month after treatment ends. Secondary outcome measures were collected at the same assessment points via pencil and paper interviews completed by subjects.
Eligibility Criteria
Inclusion Criteria:
Chronic ongoing pain (i.e., pain at all times) with an average pain intensity of at least 4/10 on 0-10 numeric rating scale
Pain is either worse or started since the onset of other MS symptoms.
Pain of at least six months duration.
Reads, speaks and understands English.
Definitive diagnosis of multiple sclerosis (MS)
At least 18 years of age
Recruited from a recruitment source approved by the IRB
Exclusion Criteria:
Severe cognitive impairment resulting in the inability to verbally comprehend, learn, and recall new auditory verbal information, as reflected by a TICS score of 20 or less.
Currently participating in counseling and/or psychotherapy more than once a week.
Currently taking anti-psychotic medications
Has been hospitalized for psychiatric reasons in the past six months
Experiencing current active suicidal ideation.
Has received treatment or participated in a clinical trial that involved significant elements of either CBT or hypnosis within the past year.
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There is 1 Location for this study
Seattle Washington, 98195, United States
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