Multiple Sclerosis Clinical Trial

Prospective Investigation of Multiple Sclerosis in the Three Rivers Region

Summary

In this longitudinal prospective natural history study of multiple sclerosis (MS), the overarching goal is to understand the factors that influence individual variation in disease trajectory and treatment response and pave the way for realizing precision medicine in MS. Because MS is a chronic neurological disorder, this observational cohort study will span a 30-year time frame.

View Full Description

Full Description

Research Activities: Initial Questionnaire, Questionnaire for Self-Reported Outcomes, Biological Sample Collection (Blood, Stool, Urine, Cerebrospinal fluid), Genetic Analysis, Standard Quantitative Assessment of Function, Cognitive Assessment, Neuroimaging, Biometric Sensors, Social Network Questionnaire, Connor-Davidson Resilience Scale, NEO Five-Factor Inventory, and the COVID19 Response Surveys.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Inclusion criteria for MS patients include:

willing and able to give consent
age 7 years or older
diagnosis of multiple sclerosis or related disorders, including a first central nervous system demyelinating episode with a positive MRI scan or abnormal MRI scans characteristic of MS but no clinical symptoms of the disease

For healthy controls:

Age 7 years or older
Willing and able to provide consent (for >=18 years) or assent with permission from at least one of the child's parents (for <18 years)
No known personal history of multiple sclerosis or related disorders
No other chronic diseases
Family members, unrelated household controls, or controls from the general population could be eligible

There is no exclusion criteria.

Study is for people with:

Multiple Sclerosis

Estimated Enrollment:

7500

Study ID:

NCT02994121

Recruitment Status:

Recruiting

Sponsor:

University of Pittsburgh

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There is 1 Location for this study

See Locations Near You

University of Pittsburgh
Pittsburgh Pennsylvania, 15260, United States More Info
Zongqi Xia, MD, PhD
Contact
412-383-5377

How clear is this clinincal trial information?

Study is for people with:

Multiple Sclerosis

Estimated Enrollment:

7500

Study ID:

NCT02994121

Recruitment Status:

Recruiting

Sponsor:


University of Pittsburgh

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.

Please confirm you are a US based health care provider:

Yes, I am a health care Provider No, I am not a health care provider