Myeloproliferative Neoplasms Clinical Trial

Long-term Safety and Efficacy of Momelotinib in Subjects With Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis, Polycythemia Vera or Essential Thrombocythemia

Summary

This open-label study is to determine the long-term safety and tolerability of momelotinib in previously enrolled study participants with primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (post-PV MF), post-essential thrombocythemia myelofibrosis (post-ET MF), polycythemia vera (PV), or essential thrombocythemia (ET), who have tolerated and achieved stable disease or better with momelotinib treatment while enrolled in a previous clinical trial.

View Eligibility Criteria

Eligibility Criteria

Key Inclusion Criteria:

Currently enrolled in study CCL09101E, or YM387-II-02, or successfully completed 24 weeks of study GS-US-352-1672
Able to comprehend and willing to sign informed consent form

Key Exclusion Criteria:

Known hypersensitivity to momelotinib, its metabolites, or formulation excipients

Note: Other protocol defined Inclusion/Exclusion criteria may apply.

Study is for people with:

Myeloproliferative Neoplasms

Phase:

Phase 2

Estimated Enrollment:

87

Study ID:

NCT02124746

Recruitment Status:

Completed

Sponsor:

Sierra Oncology LLC - a GSK company

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There is 1 Location for this study

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Scottsdale Arizona, , United States

Orange California, , United States

Stanford California, , United States

Whittier California, , United States

Jacksonville Florida, , United States

Baltimore Maryland, , United States

Boston Massachusetts, , United States

Ann Arbor Michigan, , United States

Rochester Minnesota, , United States

Saint Louis Missouri, , United States

Bronx New York, , United States

New York New York, , United States

Cleveland Ohio, , United States

Houston Texas, , United States

Salt Lake City Utah, , United States

Frankston Victoria, , Australia

Parkville Victoria, , Australia

Toronto Ontario, , Canada

Montreal Quebec, , Canada

La Tronche , , France

Paris , , France

Minden , , Germany

How clear is this clinincal trial information?

Study is for people with:

Myeloproliferative Neoplasms

Phase:

Phase 2

Estimated Enrollment:

87

Study ID:

NCT02124746

Recruitment Status:

Completed

Sponsor:


Sierra Oncology LLC - a GSK company

How clear is this clinincal trial information?

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