Myeloproliferative Neoplasms Clinical Trial

Research Tissue Bank

Summary

This study that will allow for the preservation and/or storage of a small portion one or more of the following tissues:

Peripheral blood
Bone marrow
Bone marrow biopsy
A phlebotomized unit of blood
Spleen cells
Toenail clippings

This material will be used for the study of Myeloproliferative Disorders (MPD) by researchers. The goals of this research study are to understand the causes of MPDs, how to diagnose them more easily and how to treat them better. MPD is a disease affecting hematopoietic stem cells. Hematopoietic stem cells are cells that make blood cells. These stem cells grow in the center portion of the bones called bone marrow. Under some conditions, these cells are also found in blood. There are several diseases, which are classified as MPD. These include polycythemia vera (too many red blood cells), essential thrombocythemia (too many platelets), and idiopathic myelofibrosis (abnormal blood cells and fibers build up in the bone marrow). These syndromes carry a high risk of developing leukemia. It is important to continue to learn more about these blood cancers and to learn more about the effectiveness and potential side effects of various treatments.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Patients diagnosed with Philadelphia chromosome negative myeloproliferative disorders (MPD) polycythemia vera (PV), idiopathic myelofibrosis (IM), and essential thrombocythemia (ET) are eligible.
Newly diagnose MPD patients as well as previously treated for a MPD are eligible.
Signed informed consent is required from each patient at the time of enrollment.

Exclusion Criteria:

Patients currently participating in experimental treatment arms of MPD-RC protocols, or other experimental treatment protocols are not eligible during the period they are on study.

Study is for people with:

Myeloproliferative Neoplasms

Estimated Enrollment:

963

Study ID:

NCT00666549

Recruitment Status:

Completed

Sponsor:

Icahn School of Medicine at Mount Sinai

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There are 10 Locations for this study

See Locations Near You

Palo Alto Medical Foundation Research Institute
Palo Alto California, 94301, United States
Weill Cornell University
Washington District of Columbia, 10065, United States
University of Georgetown
Washington District of Columbia, 20057, United States
University of Illinois at Chicago
Chicago Illinois, 60612, United States
Johns Hopkins
Baltimore Maryland, 21205, United States
Roswell Park
Buffalo New York, 14263, United States
Mount Sinai Medical Center
New York New York, 10029, United States
University of Pennsylvania
Philadelphia Pennsylvania, 19107, United States
University of Utah
Salt Lake City Utah, 84102, United States
Ospedali Riuniti di Bergamo
Bergamo IL, , Italy
University of Florence
Florence IL, 60302, Italy

How clear is this clinincal trial information?

Study is for people with:

Myeloproliferative Neoplasms

Estimated Enrollment:

963

Study ID:

NCT00666549

Recruitment Status:

Completed

Sponsor:


Icahn School of Medicine at Mount Sinai

How clear is this clinincal trial information?

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