Myeloproliferative Neoplasms Clinical Trial
Tissue Banking Study – Polycythemia Vera or Essential Thrombocythemia (PV & ET) Patients
Summary
The purpose of the study is to isolate and characterize stem cells of patients with Polycythemia Vera (PV) and Essential Thrombocythemia (ET) to find out why these cells are not working the way they should be and why they seem to be sensitive to regulatory factors in the blood, such as clotting.
Full Description
Specific Aim 1: Assess the effects of RG7112 on MPN HSC/HPC p53 levels and study how it affects MPN stem cell function.
Specific Aim 2. Assess the effects of a combination of low doses of IFNα and RG7112 on MPN HSC/HPC.
Eligibility Criteria
Inclusion Criteria:
polycythemia vera or essential thrombocythemia
agree to give blood for study
Exclusion Criteria:
none
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There is 1 Location for this study
New York New York, 10029, United States
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