A Comprehensive Study of Clinically Staged Pediatric Hodgkin’s Disease: Chemotherapy for All Patients; Supplementary Low Dose Involved Field Irradiation for Selected Patients (CCG 5942)
Study Hypothesis: Clinical staging without laparotomy/splenectomy is adequate for children and young adults with Hodgkin's disease who receive chemotherapy as a component of treatment.
Age less than 21 years at diagnosis Previously untreated, pathologically confirmed diagnosis of Hodgkin's disease. Informed patient/parental consent as required by individual institution and in accordance with the Dept of Health and Human Services Approval of this protocol by the individual institutional Human Subjects Review Committee. Indicate Hodgkin's disease clinical stage. Indicate presence or absence of "B" symptoms. For Stage I and II disease indicate the following: presence or absence of bulk disease number of involved nodal regions presence or absence of hilar adenopathy