Non Hodgkin Lymphoma Clinical Trial

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A Safety Study of SGN-CD19A for B-Cell Lymphoma

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Summary

This is a phase 1, open-label, dose-escalation, multicenter study to evaluate the safety and tolerability of SGN-CD19A in patients with relapsed or refractory B-lineage non-Hodgkin lymphoma (B-NHL)

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Eligibility Criteria

Inclusion Criteria:

Pathologically confirmed diagnosis of mantle cell lymphoma, follicular lymphoma Grade 3, diffuse large B-cell lymphoma (DLBCL), including transformed follicular histology, Burkitt lymphoma, or B-lineage lymphoblastic lymphoma
Relapsed, refractory, or progressive disease following at least 1 prior systemic therapy. Patients with DLBCL or follicular lymphoma Grade 3 must have also received intensive salvage therapy.
Eastern Cooperative Oncology Group status of 0 or 1
Measurable disease

Exclusion Criteria:

Allogeneic stem cell transplant (SCT)

Study is for people with:

Non Hodgkin Lymphoma

Phase:

Phase 1

Estimated Enrollment:

64

Study ID:

NCT01786135

Recruitment Status:

Completed

Sponsor:

Seagen Inc.

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There are 6 Locations for this study

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University of Alabama at Birmingham
Birmingham Alabama, 35294, United States
City of Hope National Medical Center
Duarte California, 91010, United States
Stanford Cancer Center
Stanford California, 94305, United States
H. Lee Moffitt Cancer Center & Research Institute
Tampa Florida, 33612, United States
Memorial Sloan Kettering Cancer Center
New York New York, 10021, United States
MD Anderson Cancer Center / University of Texas
Houston Texas, 77030, United States
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How clear is this clinincal trial information?

Study is for people with:

Non Hodgkin Lymphoma

Phase:

Phase 1

Estimated Enrollment:

64

Study ID:

NCT01786135

Recruitment Status:

Completed

Sponsor:


Seagen Inc.

How clear is this clinincal trial information?

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