Non Hodgkin Lymphoma Clinical Trial

Proleukin in Combination With Rituxan in Patients With Intermediate and High-Grade Non-Hodgkin’s Lymphoma.

Summary

The purpose of this study is to determine the safety and effectiveness of combination therapy with Proleukin and Rituxan on patients with intermediate-and high- grade Non-Hodgkin's lymphoma.

View Eligibility Criteria

Eligibility Criteria

Inclusion:

Diagnosis: CD20+ B-cell non-Hodgkin's lymphoma (NHL) classified as intermediate- or high-grade according to the Working Formulation, subtypes D to H. Must have measureable progressive or refractory disease after no more than three prior chemotherapy regimens.

Exclusion:

Clinically significant cardiac dysfunction, or a history of myocardial infarction or heart failure within 6 months of first study treatment
Clinically significant pulmonary dysfunction.
Liver disease (note hepatitis C seropositive subjects may be enrolled if they have no active disease as demonstrated by undetectable HCV viral loads, biopsy showing no active disease, and/or history of normal transaminases on at least three different dates within one year of first study treatment).
Symptomatic thyroid disease requiring medical intervention other than replacement treatment for hypothyroidism.
History of autoimmune disease.
History of positive serology for human immunodeficiency virus (HIV).

Study is for people with:

Non Hodgkin Lymphoma

Phase:

Phase 2

Study ID:

NCT00045864

Recruitment Status:

Completed

Sponsor:

Chiron Corporation

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There are 33 Locations for this study

See Locations Near You

ACRC/Arizona Clinical Research Center, Inc.
Tucson Arizona, 85712, United States
Hoag Cancer Center
Newport Beach California, 92658, United States
UC Davis Cancer Center
Sacramento California, 95817, United States
John Wayne Cancer Institute
Santa Monica California, 90404, United States
Stanford University Medical Center
Stanford California, 94305, United States
California Cancer Medical Center
West Covina California, 91790, United States
Georgetown University Medical Center, Lombardi Cancer Center
Washington District of Columbia, 20007, United States
Washington Cancer Institute
Washington District of Columbia, 20010, United States
Division of Hematology/Oncology, University of Miami School of Medicine
Miami Florida, 33313, United States
Northwestern University, Feinberg School of Medicine
Chicago Illinois, 60611, United States
Rush Cancer Institute
Chicago Illinois, 60612, United States
Oncology Specialists, S.C.
Park Ridge Illinois, 60068, United States
Cancer Care Center
Bloomington Indiana, 47403, United States
Consultants in Blood Disorders and Cancer
Louisville Kentucky, 40207, United States
Louisiana Health Sciences Center, Department of Medicine, Hematology/Oncology
Shreveport Louisiana, 71130, United States
Kansas City Oncology and Hematology Group
Kansas City Missouri, 64111, United States
Arch Medical Group, LLC
St. Louis Missouri, 63141, United States
Dartmouth-Hitchcock-Medical Center
Lebanon New Hampshire, 03756, United States
Our Lady of Mercy Medical Center, Comprehensive Cancer Center
Bronx New York, 10466, United States
Memorial Sloan Kettering Cancer Center
New York New York, 10021, United States
East Carolina University School of Medicine/ Division of Hematology/Oncology
Greenville North Carolina, 27858, United States
Roger Maris Health System
Fargo North Dakota, 58122, United States
Gabrail Cancer Center
Canton Ohio, 44718, United States
Oncology Hematology Care Inc.
Cincinnati Ohio, 45242, United States
The Cleveland Clinic Foundation
Cleveland Ohio, 44195, United States
Hematology /Oncology Consultants Inc.
Columbus Ohio, 43235, United States
Oregon Heath and Science University
Portland Oregon, 97201, United States
University of Pennsylvania
Philadelphia Pennsylvania, 19104, United States
Cancer Centers of the Carolinas
Greenville South Carolina, 29615, United States
Germantown Cancer Center
Germantown Tennessee, 38138, United States
Vanderbilt University Medical Center
Nashville Tennessee, 37232, United States
Cancer Specialists of South Texas, P.A.
Corpus Christi Texas, 78412, United States
Virginia Cancer Institute
Richmond Virginia, 23230, United States

How clear is this clinincal trial information?

Study is for people with:

Non Hodgkin Lymphoma

Phase:

Phase 2

Study ID:

NCT00045864

Recruitment Status:

Completed

Sponsor:


Chiron Corporation

How clear is this clinincal trial information?

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