Ovarian Cancer Clinical Trial

A Study of Atezolizumab Versus Placebo in Combination With Paclitaxel, Carboplatin, and Bevacizumab in Participants With Newly-Diagnosed Stage III or Stage IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Summary

This is a Phase III, global, double-blind, 2-arm randomized study designed to compare the efficacy and safety of atezolizumab + paclitaxel + carboplatin + bevacizumab versus placebo + paclitaxel + carboplatin + bevacizumab. Study participants will have Stage 3 or 4 ovarian cancer (OC), fallopian tube cancer (FTC), or primary peritoneal cancer (PPC) with macroscopic residual disease postoperatively (i.e., after primary tumor reductive surgery) or who will undergo neoadjuvant therapy followed by interval surgery.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Participants receiving a histologic diagnosis of epithelial ovarian cancer (EOC), peritoneal primary carcinoma, or fallopian tube cancer
Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1, or 2
Life expectancy greater than (>) 12 weeks
For participants who receive therapeutic anticoagulation: stable anticoagulant regimen
Availability of a representative formalin-fixed, paraffin-embedded (FFPE) tumor specimen in paraffin blocks (preferred) or at least 20 unstained slides (for detailed tissue requirements at screening)

Exclusion Criteria:

Received a current diagnosis of borderline epithelial ovarian tumor (formerly tumors of low malignant potential)
Have recurrent invasive epithelial ovarian, fallopian tube, or primary peritoneal cancer that was treated only with surgery (example [e.g.], participants with Stage IA or Stage IB epithelial ovarian or fallopian tube cancers)
Have non-epithelial ovarian tumors (e.g., germ cell tumors, sex cord stromal tumors)
Received prior radiotherapy to any portion of the abdominal cavity or pelvis
Received prior chemotherapy for any abdominal or pelvic tumor that include neoadjuvant chemotherapy (NACT) for ovarian, primary peritoneal or fallopian tube cancer
Received any biological and/or targeted therapy (including but not limited to vaccines, antibodies, tyrosine kinase inhibitors) or hormonal therapy for management and/or treatment of epithelial ovarian or peritoneal primary cancer
Have synchronous primary endometrial cancer
Have a prior history of primary endometrial cancer, except: Stage IA cancer; superficial myometrial invasion, without lymphovascular invasion; grade less than (<) 3 or poorly differentiated subtypes, and this includes papillary serous, clear cell or other International Federation of Gynecological Oncologists (FIGO) Grade 3 lesions
With the exception of non-melanoma skin cancer and other specific malignancies as noted above, other invasive malignancies with any evidence of other cancers present within the last 5 years or previous cancer treatment that contraindicates this protocol therapy
Have a known hypersensitivity or allergy to biopharmaceutical agents produced in Chinese hamster ovary cells or any component of the atezolizumab and/or bevacizumab formulations
Undergo major surgical procedure within 28 days prior to first bevacizumab dose, or anticipation of the need for a major surgical procedure during the course of the study except participants who receive NACT and will need interval surgery. This may include but is not limited to laparotomy.
Have prior allogeneic bone marrow transplantation or solid organ transplant
Have any other diseases, metabolic dysfunction, physical examination finding, or clinical laboratory finding giving reasonable suspicion of a disease or condition that contraindicates the use of an investigational drug or that may affect the interpretation of the results
Have any approved or investigational anti-cancer therapy, including chemotherapy or hormonal therapy, with exceptions: Hormone-replacement therapy or oral contraceptives
Are administered treatment with any other investigational agent or participation in another clinical study with anti-cancer therapeutic intent
Have core biopsy or other minor surgical procedures within 7 days prior to the first dose of bevacizumab
Have known sensitivity to any component of bevacizumab
Have known sensitivity to any component of paclitaxel
Current treatment with anti-viral therapy for hepatitis B virus (HBV)
History of leptomeningeal disease

Study is for people with:

Ovarian Cancer

Phase:

Phase 3

Estimated Enrollment:

1301

Study ID:

NCT03038100

Recruitment Status:

Completed

Sponsor:

Hoffmann-La Roche

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There are 259 Locations for this study

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St. Joseph'S Hospital & Medical Center
Phoenix Arizona, 85013, United States
Arizona Oncology Associates, PC - HAL; Arizona Oncology Associates, PC - HAL
Scottsdale Arizona, 85258, United States
Arizona Oncology - HOPE Wilmot
Tucson Arizona, 85710, United States
Moores Cancer Center at UC San Diego Health
La Jolla California, 92093, United States
LAC + USC Medical Center
Los Angeles California, 90033, United States
UCLA - School of Medicine
Los Angeles California, 90095, United States
Kaiser Permanente - Oakland
Oakland California, 94611, United States
The Center for Cancer Prevention and Treatment at St.Joseph Hospital of Orange
Orange California, 92868, United States
UC Irvine Medical Center
Orange California, 92868, United States
Stanford University
Palo Alto California, 94305, United States
Kaiser Permanente - Sacramento
Roseville California, 95661, United States
Southern California Kaiser Permanente
San Diego California, 92108, United States
California Pacific Medical Center Research Institute
San Francisco California, 94115, United States
K. Permanente - San Fransisco
San Francisco California, 94115, United States
University of California San Francisco Cancer Center
San Francisco California, 94158, United States
Kaiser Permanente - Santa Clara
Santa Clara California, 95051, United States
Olive View/Ucla Medical Center
Sylmar California, 91342, United States
Kaiser Permanente - Walnut Creek
Walnut Creek California, 94596, United States
University of Colorado Hospital - Anschutz Cancer Pavilion
Aurora Colorado, 80045, United States
Danbury Hospital
Danbury Connecticut, 06810, United States
Eastern Connecticut Hematology and Oncology Associates; (ECHO)
Norwich Connecticut, 06360, United States
Sylvester Comprehensive Cent.
Miami Florida, 33136, United States
Miami Cancer Institute of Baptist Health, Inc.
Miami Florida, 33176, United States
Women's Cancer Associates
Saint Petersburg Florida, 33701, United States
Sarasota Memorial Health Care System; Cancer Research Program
Sarasota Florida, 34239, United States
Northside Hospital
Atlanta Georgia, 30342, United States
Northeast Georgia Medical Center; Oncology Research Dept-5C
Gainesville Georgia, 30501, United States
Women's Cancer Center
Honolulu Hawaii, 96826, United States
Rush University Medical Center
Chicago Illinois, 60612, United States
Univ of Chicago
Chicago Illinois, 60637, United States
Sudarshan K. Sharma, MD, Ltd.
Hinsdale Illinois, 60521, United States
Parkview Research Center
Fort Wayne Indiana, 46845, United States
St.Vincent Health System; Gynecologic Oncology
Indianapolis Indiana, 46260, United States
University of Iowa Hospital & Clinic; Division of Hematology/Oncology
Iowa City Iowa, 52242, United States
University of Kentucky; Gynecologic Oncology
Lexington Kansas, 40536, United States
St. Elizabeth Edgewood; Cancer Care Center" for Account St. Elizabeth Edgewood
Edgewood Kentucky, 41017, United States
Woman's Hospital
Baton Rouge Louisiana, 70817, United States
Maine Medical Partners Women's Health; Gyn-Oncology
Scarborough Maine, 04074, United States
Greater Baltimore Medical Center
Baltimore Maryland, 21204, United States
Sinai Hospital of Baltimore
Baltimore Maryland, 21215, United States
Weinberg CA Inst Franklin Sq
Baltimore Maryland, 21237, United States
Frederick Health Hospital
Frederick Maryland, 21701, United States
Massachusetts General Hospital
Boston Massachusetts, 02114, United States
Baystate Medical Center
Springfield Massachusetts, 01199, United States
St. Joseph Mercy Hospital
Ann Arbor Michigan, 48106, United States
Karmanos Cancer Institute
Detroit Michigan, 48201, United States
Munson Medical Center
Traverse City Michigan, 49684, United States
Sanford Health Bemidji
Bemidji Minnesota, 56601, United States
University of Minnesota
Minneapolis Minnesota, 55455, United States
Metro-Minnesota Community Oncology Research Consortium
Saint Louis Park Minnesota, 55416, United States
Minnesota Oncology Hematology Woodbury
Woodbury Minnesota, 55125, United States
St. Dominic-Jackson Memorial Hospital
Jackson Mississippi, 39216, United States
Washington University School of Medicine; Dept of Medicine/Div of Medical Oncology
Saint Louis Missouri, 63108, United States
Billings Clinic; Cancer Center
Billings Montana, 59101, United States
Community Cancer Care
Missoula Montana, 59804, United States
Nebraska Methodist Hospital
Omaha Nebraska, 68114, United States
University of Nebraska Medical Center
Omaha Nebraska, 68198, United States
Women's Cancer Center
Las Vegas Nevada, 89106, United States
Center of Hope
Reno Nevada, 89511, United States
Dartmouth Hitchcock Medical Center
Lebanon New Hampshire, 03756, United States
MSK @Basking Ridge
Basking Ridge New Jersey, 07920, United States
Cooper Health System; MD Anderson Cancer Center
Camden New Jersey, 08103, United States
John Theurer Cancer Center at Hackensack University Medical Center
Hackensack New Jersey, 07601, United States
Memorial Sloan Kettering Cancer Center; MSK Monmouth
Middletown New Jersey, 07748, United States
Jersey Shore Med Ctr; OB/GYN
Neptune New Jersey, 07753, United States
Holy Name Hospital
Teaneck New Jersey, 07666, United States
Southwest Gynecologic Oncology Associates, Inc.
Albuquerque New Mexico, 87106, United States
University of New Mexico Cancer Center
Albuquerque New Mexico, 87131, United States
Womens Cancer Care Association
Albany New York, 12208, United States
New York Presbyterian Queens
Flushing New York, 11355, United States
Northwell Health; Monter Cancer Center
Lake Success New York, 11042, United States
New York Univ Medical Center; Obstetrics & Gynecolog
New York New York, 10016, United States
Mount Sinai Downtown Chelsea Centre
New York New York, 10029, United States
Icahn School of Medicine at Mount Sinai
New York New York, 10029, United States
Memorial Sloan Kettering Cancer Center
New York New York, 10065, United States
Memorial Sloan-Kettering CC
Uniondale New York, 11553, United States
Levine Cancer Institute
Charlotte North Carolina, 28204, United States
Novant Health Presbyterain Medical Center
Charlotte North Carolina, 28204, United States
Duke Medical Center
Durham North Carolina, 27710, United States
Forsythe Memorial Hospital Inc., dba Novant Health Oncology Specialists
Winston-Salem North Carolina, 27103, United States
Wake Forest Baptist Medical Center
Winston-Salem North Carolina, 27157, United States
Sanford Health Bismarck
Bismarck North Dakota, 58506, United States
Sanford Roger Maris Cancer Center
Fargo North Dakota, 58102, United States
University of Cincinnati
Cincinnati Ohio, 45203, United States
Cleveland Clinic
Cleveland Ohio, 44106, United States
Univ Hospitals of Cleveland
Cleveland Ohio, 44106, United States
Fairview Hospital; Cleveland Clinic Cancer Center
Cleveland Ohio, 44111, United States
Columbus NCORP
Columbus Ohio, 43125, United States
Ohio State University, Arthur James Cancer Hospital
Columbus Ohio, 43210, United States
Kettering Medical Center
Kettering Ohio, 45429, United States
University of Oklahoma; Stephenson Oklahoma Canc Ctr
Oklahoma City Oklahoma, 73104, United States
Oklahoma Cancer Specialists and Research Institute
Tulsa Oklahoma, 74146, United States
Oncology Associates of Oregon, P.C.; Willamette Valley Cancer Institute
Springfield Oregon, 97477, United States
Northwest Cancer Specialists, P.C.
Tigard Oregon, 97223, United States
University of Pennsylvania Health System; Cancer Center
Philadelphia Pennsylvania, 19104, United States
Thomas Jefferson University
Philadelphia Pennsylvania, 19107, United States
Temple University Hospital
Philadelphia Pennsylvania, 19140, United States
Magee-Woman's Hospital
Pittsburgh Pennsylvania, 15213, United States
Western Pennsylvania Hospital
Pittsburgh Pennsylvania, 15224, United States
Abington Mem Hosp-Abington; Rose. Can Ctr,Gyn Onc Ins
Willow Grove Pennsylvania, 19090, United States
WellSpan Gynecologic Oncology
York Pennsylvania, 17403, United States
Women & Infants Hospital
Providence Rhode Island, 02905, United States
Bon Secours - St. Francis Hospital
Greenville South Carolina, 29607, United States
Monument Health Rapid City Hospital, Inc.
Rapid City South Dakota, 57701, United States
Sanford Health System
Sioux Falls South Dakota, 57105, United States
Dell Seton Medical Center at UT-Seton Infusion Center; Research Department
Austin Texas, 78701, United States
Texas Oncology Cancer Center
Austin Texas, 78731, United States
Texas Oncology
Bedford Texas, 76022, United States
UT Southwestern Medical Center at Dallas; Department of Pathology
Dallas Texas, 75390, United States
Texas Oncology, P.A. - Fort Worth
Fort Worth Texas, 76104, United States
The University of Texas MD Anderson Cancer Center
Houston Texas, 77030, United States
Houston Methodist Hospital
Houston Texas, 77030, United States
Rocky Mountain Cancer Centers, LLP
Irving Texas, 75063, United States
Texas Oncology San Antonio Medical Center
San Antonio Texas, 78240, United States
Texas Oncology, P.A.
The Woodlands Texas, 77060, United States
Texas Oncology, P.A. - Tyler; Tyler Cancer Center
Tyler Texas, 75702, United States
Dixie Medical Center
Saint George Utah, 84790, United States
Huntsman Cancer Institute; Oncology
Salt Lake City Utah, 84112, United States
University of Virginia
Charlottesville Virginia, 22906, United States
Virginia Cancer Specialists, PC
Fairfax Virginia, 22031, United States
Virginia Oncology Associates
Norfolk Virginia, 23502, United States
Henrico Doctors' Hospital - Forest
Richmond Virginia, 23229, United States
Shenandoah Oncology Associates
Winchester Virginia, 22601, United States
University of Washington Seattle Cancer Care Alliance
Seattle Washington, 98195, United States
University of Wisconsin Hospital and Clinics
Madison Wisconsin, 53792, United States
DN Greenwald Center; DN Greenwald Center
Mukwonago Wisconsin, 53149, United States
Aspirus Regional Cancer Center
Wausau Wisconsin, 54401, United States
The Royal North Shore Hospital; Northern Sydney Cancer Centre
St Leonards New South Wales, 2065, Australia
Cabrini Hospital; Cabrini Foundation
Malvern Victoria, 3144, Australia
Peter MacCallum Cancer Center
North Melbourne Victoria, 3051, Australia
Krankenhaus Der Barmherzigen Brüder Graz; Gynäkologie
Graz , 8020, Austria
Tiroler Landeskrankenanstalten Ges.M.B.H.; Abt. Für Gynäkologie
Innsbruck , 6020, Austria
Landeskrankenhaus Salzburg; Gynäkologie Und Onkologie
Salzburg , 5020, Austria
Medizinische Universität Wien; Univ.Klinik für Frauenheilkunde - Klinik für Gynäkologie
Wien , 1090, Austria
AZ Maria Middelares
Gent , 9000, Belgium
UZ Gent
Gent , 9000, Belgium
UZ Leuven Gasthuisberg
Leuven , 3000, Belgium
Sint Augustinus Wilrijk
Wilrijk , 2610, Belgium
Instituto Nacional de Cancer - INCa; Oncologia
Rio de Janeiro RJ, 20560, Brazil
Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda
Sao Paulo SP, 01317, Brazil
Peking Union Medical College Hospital
Beijing City , 10003, China
Beijing Cancer Hospital
Beijing , 10014, China
West China Second University Hospital
Chengdu City , 61006, China
Chongqing Cancer Hospital
Chongqing , 40003, China
Sun Yet-sen University Cancer Center
Guangzhou City , 51066, China
Women's hospital school of medicine Zhejiang University
Hangzhou , 31000, China
Harbin Medical University Cancer Hospital
Harbin , 15008, China
Jiangsu Province Hospital (the First Affiliated Hospital With Nanjing Medical University)
Nanjing City , 21002, China
Zhongda Hospital Affiliated to Southeast University
Nanjing , 21000, China
Guangxi Cancer Hospital of Guangxi Medical University
Nanning , 53002, China
Fudan University Shanghai Cancer Center
Shanghai City , 20012, China
Tianjin Central Hospital of Gynecology Obstetrics.
Tianjin City , 30005, China
Zhejiang Cancer Hospital
Zhejiang , 31002, China
Henan Cancer Hospital
Zhengzhou , 45000, China
Fakultni nemocnice Olomouc; Onkologicka klinika
Olomouc , 779 0, Czechia
University Hospital Ostrava; Fakultní nemocnice
Ostrava-Poruba , 70852, Czechia
Gynekologicko-porodnicka klinika
Prague , 120 0, Czechia
Onkologicka klinika UK 2.LF a FN v Motole
Praha 5 , 15006, Czechia
Rigshospitalet; Onkologisk Klinik
København Ø , 2100, Denmark
Kuopio University Hospital
Kuopio , 70211, Finland
Tampereen yliopistollinen sairaala
Tampere , 33520, Finland
Turku Uni Central Hospital; Gynaecology Dept
Turku , 20521, Finland
Clinique Sainte Catherine; Hopital De Semaine
Avignon , 84918, France
Ctr Jean Bernard Clin V. Hugo; Service d'Oncologie Méd
Le Mans , 72000, France
Centre Léon Bérard; Centre régional; le cancer Rhône-Alpes
Lyon , 69373, France
l'Hôpital privé du Confluent SAS
Nantes , 44202, France
Hopital Des Diaconesses; Oncologie
Paris , 75571, France
Centre Hospitalier Lyon Sud
Pierre Benite , 69495, France
Centre Rene Huguenin; CONSULT SPECIALISEES
St Cloud , 92210, France
Institut Gustave Roussy
Villejuif , 94805, France
Campus Virchow-Klinikum Charité; Centrum 17; Klinik für Gynäkologie
Berlin , 13353, Germany
Universitätsklinikum Dresden; Klinik für Frauenheilkunde und Geburtshilfe
Dresden , 01307, Germany
Universitätsklinikum Essen; Zentrum Für Frauenheilkunde
Essen , 45122, Germany
Kliniken Essen Mitte Evang. Huyssens Stiftung/Knappschaft GmbH
Essen , 45136, Germany
Universitätsklinikum Freiburg; Frauenklinik
Freiburg , 79106, Germany
Universitätsklinikum Greifswald; Klinik für Frauenheilkunde und Brustzentrum
Greifswald , 17475, Germany
Universitätsklinikum Hamburg-Eppendorf (UKE); Klinik und Poliklinik für Gynäkologie
Hamburg , 20246, Germany
Medizinische Hochschule Hannover, Klinik für Frauenheilkunde und Geburtshilfe
Hannover , 30625, Germany
Universitätsklinikum Heidelberg; Nationales Centrum für Tumorerkrankungen (NCT)
Heidelberg , 69120, Germany
Klinikum Konstanz, Frauenklinik
Konstanz , 78464, Germany
Universitätsklinikum Schleswig-Holstein / Campus Lübeck; Klinik für Frauenheilkunde und Geburtshilfe
Lübeck , 23538, Germany
Universitätsmedizin Mainz; Klinik u. Poliklinik f. Geburtshilfe u. Frauenheilkunde
Mainz , 55131, Germany
Klinikum der Universität München; Campus Großhadern; Klinik und Poliklinik für Frauenheilkunde
Muenchen , 81377, Germany
Klinikum rechts der Isar der TU München; Klinik und Poliklinik für Frauenheilkunde
München , 81675, Germany
Klinikum Südstadt
Rostock , 18059, Germany
Universitätsklinikum Ulm Am Michelsberg; Frauenklinik
Ulm , 89075, Germany
HELIOS Dr. Horst Schmidt Kliniken Wiesbaden; Klinik für Gynäkologie und gynäkologische Onkologie
Wiesbaden , 65199, Germany
Alexandras Hospital; Dept. of Clin. Therapeutics, Athens Uni School of Medicine
Athens , 115 2, Greece
Uni Hospital of Ioannina; Oncology Dept.
Ioannina , 455 0, Greece
Agioi Anargyroi Cancer Hospital; 2Nd Oncology Dept.
Kifisia , 145 6, Greece
University Hospital of Patras Medical Oncology
Patras , 265 0, Greece
EUROMEDICA General Clinic of Thessaloniki; Medical Oncology Dept - Oncomedicare
Thessaloniki , 546 4, Greece
Hillel Yaffe MC; Gynaecology
Hadera , 38101, Israel
Shaare Zedek Medical Center; Oncology Dept
Jerusalem , 91031, Israel
Meir Medical Center; Obstetrics and Gynecology
Kfar Saba , 44281, Israel
Chaim Sheba Medical Center; Obstetrics and Gynecology
Ramat Gan , 52621, Israel
Kaplan Medical Center; Oncology Inst.
Rehovot , 76100, Israel
Azienda Ospedaliera Universitaria Federico II
Napoli Campania, 80131, Italy
ISTITUTO NAZIONALE TUMORI IRCCS FONDAZIONE G. PASCALE; Dipartimento Uro-Ginecologico
Napoli Campania, 80131, Italy
Policlinico S.Orsola-Malpighi; Istituto Oncologia R. Addarii
Bologna Emilia-Romagna, 40138, Italy
Ospedale Degli Infermi - Faenza; Oncologia Medica
Faenza Emilia-Romagna, 48018, Italy
IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola; Oncologia Medica
Meldola Emilia-Romagna, 47014, Italy
Arcispedale Santa Maria Nuova; Oncologia
Reggio Emilia Emilia-Romagna, 42100, Italy
Policlinico A. Gemelli e C.I.C.; Area Salute della Donna
Roma Lazio, 00168, Italy
A.O.Spedali Civili; Ostetricia e Ginecologia
Brescia Lombardia, 25123, Italy
IRCCS S. Raffaele; Ginecologia Oncologica
Milano Lombardia, 20132, Italy
Istituto Nazionale dei Tumori; Divisione Oncologia Chirurgica e Ginecologica
Milano Lombardia, 20133, Italy
Irccs Istituto Europeo Di Oncologia (IEO); Oncologia Medica
Milano Lombardia, 20141, Italy
Asst Grande Ospedale Metropolitano Niguarda; Dipartimento Di Ematologia Ed Oncologia
Milano Lombardia, 20162, Italy
A.O. San Gerardo; Ginecologia
Monza Lombardia, 20052, Italy
A. O. Città della Salute e della Scienza; Unità di Oncologia Ginecologica
Torino Piemonte, 10126, Italy
Ospedale Mauriziano Umberto 1; Ginecologia - Oncologia
Torino Piemonte, 10128, Italy
Ospedale Antonio Perrino; Oncologia Medica
Brindisi Puglia, 72100, Italy
Ospedale Silvestrini; Oncologia ed Ematologia
Perugia Umbria, 06123, Italy
IRCCS Istituto Oncologico Veneto (IOV); Oncologia Medica Seconda
Padova Veneto, 35128, Italy
Nagoya University Hospital
Aichi , 466-8, Japan
National Hospital Organization Shikoku Cancer Center
Ehime , 791-0, Japan
Ehime University Hospital
Ehime , 791-0, Japan
NHO Kyushu Cancer Center
Fukuoka , 811-1, Japan
Kyushu University Hospital
Fukuoka , 812-8, Japan
Kurume University Hospital
Fukuoka , 830-0, Japan
Kure Medical Center
Hiroshima , 737-0, Japan
National Hospital Organization Hokkaido Cancer Center
Hokkaido , 003-0, Japan
Hyogo Cancer Center
Hyogo , 673-0, Japan
Iwate Medical University Hospital
Iwate , 028-3, Japan
Kagoshima University Hospital
Kagoshima , 890-8, Japan
Yokohama City University Hospital
Kanagawa , 236-0, Japan
Kyoto University Hospital
Kyoto , 606-8, Japan
Mie University Hospital
Mie , 514-8, Japan
Tohoku University Hospital
Miyagi , 980-8, Japan
Niigata University Medical & Dental Hospital
Niigata , 951-8, Japan
Osaka International Cancer Institute
Osaka , 541-8, Japan
Shizuoka Cancer Center
Shizuoka , 411-8, Japan
The Jikei University Hospital
Tokyo , 105-8, Japan
The University of Tokyo Hospital
Tokyo , 113-8, Japan
The Cancer Institute Hospital of JFCR
Tokyo , 135-8, Japan
Keio University Hospital
Tokyo , 160-8, Japan
National Cancer Center
Goyang-si , 10408, Korea, Republic of
Seoul National University Hospital
Seoul , 03080, Korea, Republic of
Asan Medical Center
Seoul , 05505, Korea, Republic of
Samsung Medical Center
Seoul , 06351, Korea, Republic of
Oslo Universitetssykehus HF; Radiumhospitalet
Oslo , 0310, Norway
St. Olavs Hospital
Trondheim , 7006, Norway
Centrum Onkologii Instytut im. M.Sklodowskiej-Curie; Klinika Ginekologii Onkologicznej
Krakow , 31-11, Poland
Szpital Kliniczny im. Heliodora Święcickiego UM w Poznaniu; Oddział Ginekologii Onkologicznej
Poznań , 60-56, Poland
Icu Spsk - 2
Szczecin , 70-11, Poland
Narodowy Instytut Onkologii im. M.Sklodowskiej-Curie;Klinika Ginekologii Onkologicznej
Warszawa , 02-78, Poland
Moscow City Oncology Hospital #62
Moscovskaya Oblast Moskovskaja Oblast, 14342, Russian Federation
Clinical Oncology Dispensary of Ministry of Health of Tatarstan
Kazan , 42002, Russian Federation
N.N.Burdenko Main Military Clinical Hospital; Oncology Dept
Moscow , 10522, Russian Federation
St. Petersburg Oncology & Gynecology; City Clinical Oncology Dispensary
Saint-Petersburg , 19702, Russian Federation
Corporacio Sanitaria Parc Tauli; Servicio de Oncologia
Sabadell Barcelona, 8208, Spain
Hospital Universitario Son Espases
Palma de Mallorca Islas Baleares, 07010, Spain
Fundacion Hospital de Alcorcon; Servicio de Oncologia
Alcorcon Madrid, 28922, Spain
Hospital Universitari Dexeus - Grupo Quironsalud; Servicio de Oncologia Medica
Barcelona , 08028, Spain
Hospital General Universitario Gregorio Marañon; Servicio de Oncologia
Madrid , 28007, Spain
Centro Integral Oncologico Clara Campal; Servicio de Oncología
Madrid , 28050, Spain
Hospital Clinico Universitario Virgen de la Victoria; Servicio de Oncologia
Malaga , 29010, Spain
Hospital Universitario la Fe; Servicio de Oncologia
Valencia , 46026, Spain
Hospital Universitario Miguel Servet; Servicio Oncologia
Zaragoza , 50009, Spain
Uni Hospital Linkoeping; Dept. of Oncology
Linköping , 58185, Sweden
Karolinska Hospital; Oncology - Radiumhemmet
Stockholm , 171 7, Sweden
Baskent University Adana Dr. Turgut Noyan Practice and Research Hospital; Medical Oncology
Adana , 01230, Turkey
Ankara University Medical Faculty; Medikal Onkoloji
Ankara , 06100, Turkey
Baskent Universitesi Ankara Hastanesi; Tıbbi Onkoloji Bölümü
Ankara , 06490, Turkey
Koc University Medical Faculty; Department of Gynecology & Obstetrics
Istanbul , 34010, Turkey
Istanbul Uni Istanbul Medical Faculty
Istanbul , 34093, Turkey
Istanbul University Cerrahpasa Medical Faculty; Obstetrics and Gynecology
Istanbul , 34098, Turkey

How clear is this clinincal trial information?

Study is for people with:

Ovarian Cancer

Phase:

Phase 3

Estimated Enrollment:

1301

Study ID:

NCT03038100

Recruitment Status:

Completed

Sponsor:


Hoffmann-La Roche

How clear is this clinincal trial information?

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