Ovarian Cancer Clinical Trial
Choosing Ovarian Preservation or Removal Before Surgery for Endometrial Cancer
The purpose of this study is to learn more about the factors that influence decision-making before surgery (distress about cancer and/or reproductive concerns) and the possibility of regret after surgery.
Women aged ≥ 18 and ≤ 50 years
Endometrioid histological diagnosis
Scheduled for surgical intervention at MSKCC
FIGO grade 1-2, clinical stage I
Disease confined to uterus, no clear evidence of deep (≥50%) myoinvasion on imaging (MRI preferred, ultrasound optional)
Normal ovaries on preoperative imaging
Able to provide informed consent
Known Lynch syndrome
Prior bilateral oophorectomy
Personal history of hormone receptor-positive breast carcinoma
Increased risk of ovarian cancer identified on the basis of family or personal history
Women currently on hormonal contraception, letrozole, or tamoxifen may not opt-in to AMH
Women who recently underwent ovarian stimulation within the past 3 months may not opt-in to AMH
Women who have pituitary dysfunction (or any pituitary disorders) may not opt-in to AMH
Women who completed chemotherapy within <12 months may not opt-in to AMH
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