Ovarian Cancer Clinical Trial

Doxil and Gemcitabine in Recurrent Ovarian Cancer

Summary

Standard treatment for recurrent ovarian cancer is chemotherapy with one or more drugs. One of these drugs, Doxil, can cause skin toxicity at the standard dosages. This study investigates using a lower dose given more frequently in combination with a second drug Gemcitabine.

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Full Description

This study will evaluate the toxicities of Doxil and Gemcitabine given on an every two week basis. Our hypothesis is that toxicity will be less than that with standard dosing without any negative effect on survival. Patients will also be evaluated with CT scans every 3 months. Toxicity will be assessed with every cycle of treatment. Treatment will continue until toxicity or signs of progression.

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Eligibility Criteria

Inclusion Criteria:

recurrent platinum resistant ovarian cancer
measurable disease

Exclusion Criteria:

prior treatment with Doxil or Gemzar
life expectancy <3months
cardiac ejection fraction <50%

Study is for people with:

Ovarian Cancer

Phase:

Phase 2

Estimated Enrollment:

24

Study ID:

NCT00312650

Recruitment Status:

Terminated

Sponsor:

Women and Infants Hospital of Rhode Island

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There is 1 Location for this study

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Women and Infants' Hospital
Providence Rhode Island, 02905, United States

How clear is this clinincal trial information?

Study is for people with:

Ovarian Cancer

Phase:

Phase 2

Estimated Enrollment:

24

Study ID:

NCT00312650

Recruitment Status:

Terminated

Sponsor:


Women and Infants Hospital of Rhode Island

How clear is this clinincal trial information?

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