Ovarian Cancer Clinical Trial
Primary Tumor Harvest for the Purpose of Possible Use in a Future Clinical Trial in Patients With Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Summary
The purpose of this research study is to collect tumor samples at the time of surgery and store them for possible use as part of an experimental vaccine study for the participants cancer in the future.
Full Description
Even if tumor sample is collected, the participant is under no obligation to participate in the vaccine study.
Participants will have their regularly planned surgery as described by their surgeon. During the surgery, tumor samples will be collected. We will only collect tumor that is not needed and could otherwise be thrown away.
The tumor samples will be frozen and placed in storage for up to two years.
Eligibility Criteria
Inclusion Criteria:
Clinical suspicion of advanced ovarian, fallopian tube or primary peritoneal cancer as determined by a gynecologic oncologist
Patients are planning to undergo primary or secondary debulking surgery as part of standard of care for their disease
Estimated life expectancy of 6 months or greater
18 years of age or older
Exclusion Criteria:
More than one prior chemotherapy regimen
Serious intercurrent illness such as infection requiring IV antibiotics, or significant cardiac disease characterized by significant arrhythmia, unstable ischemic coronary disease or congestive heart failure
Known HIV infection
Active second malignancy, aside from basal cell or squamous cell carcinoma of the skin
Significant autoimmune disease, including psoriasis
History of clinically significant venous thromboembolism
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There are 3 Locations for this study
Boston Massachusetts, 02114, United States
Boston Massachusetts, 02115, United States
Boston Massachusetts, 02115, United States
Boston Massachusetts, 02215, United States
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