Ovarian Cancer Clinical Trial

Salpingectomy at Cesarean Delivery for Ovarian Cancer Reduction (SCORE)

Summary

To compare the feasibility and surgical outcomes between complete salpingectomy and standard postpartum tubal ligation (partial salpingectomy) at the time of cesarean delivery in women with undesired future fertility. as a possible ovarian cancer risk-reducing procedure.

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Full Description

All pregnant women receiving prenatal care within the UAB Health System, and planning to undergo tubal ligation at the time of their scheduled cesarean delivery (primary or repeat) will be approached about the study. Patients will be randomized to receive either the standard tubal ligation practice at our institution (modified Pomeroy procedure or Parkland) or a complete salpingectomy. The objective of this trial is to evaluate if a complete salpingectomy can be performed safely and comparable to a standard postpartum tubal ligation.

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Eligibility Criteria

Inclusion Criteria:

All pregnant women > 25 years receiving prenatal care within the UAB Health System, and planning to undergo tubal ligation at the time of their scheduled cesarean delivery (primary or repeat)
Informed consent obtained

Exclusion Criteria:

Inability to obtain informed consent
Fetal death or anomalies
Preterm delivery < 36 weeks gestation
Immune-compromising disease
Chronic steroid use
Chronic prophylactic or therapeutic anti-coagulation
Patients no followed in our regional health system
Known BRCA mutation carrier status
Age < 25 years

Study is for people with:

Ovarian Cancer

Estimated Enrollment:

80

Study ID:

NCT02374827

Recruitment Status:

Completed

Sponsor:

University of Alabama at Birmingham

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There is 1 Location for this study

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University of Alabama at Birmingham
Birmingham Alabama, 35249, United States

How clear is this clinincal trial information?

Study is for people with:

Ovarian Cancer

Estimated Enrollment:

80

Study ID:

NCT02374827

Recruitment Status:

Completed

Sponsor:


University of Alabama at Birmingham

How clear is this clinincal trial information?

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