Ovarian Cancer Clinical Trial

Specimen and Data Study for Ovarian Cancer Early Detection and Prevention

Summary

RATIONALE: To improve strategies for detection and prevention of early-stage disease.

PURPOSE: This research study is collecting specimens and data to develop better methods for early detection and prevention of ovarian cancer among the high risk population and those who have the disease.

View Full Description

Full Description

OBJECTIVES:

To identify and develop highly sensitive and specific tumor markers for the detection and management of ovarian cancer and other gynecological malignancies.
To identify new prevention approaches and therapies.
To identify measures to improve the quality of life for women at increased risk for developing the disease and for women diagnosed with ovarian cancer.

OUTLINE: Subjects undergo periodic specimen and data collection for research studies, including molecular, biochemical, functional, and genetic marker studies. Participants may have samples of blood, tissue, or body fluids (such as ascites, pleural fluid or urine), or any combination of the aforementioned samples obtained to develop tumor markers to detect early stage or recurrent ovarian cancer.

The results from the biomarker research studies will not be reported to the patient or the physician. In the future, if any of the experimental tumor markers are found to be effective in detecting early stage ovarian cancer, and the patient's result is abnormal, the patient and physician will be notified.

Subjects may be asked to complete a combination of questionnaires designed to evaluate psychological functioning among women enrolled in a comprehensive ovarian cancer early detection program who are at increased risk for developing disease as compared to women currently diagnosed with ovarian cancer.

View Eligibility Criteria

Eligibility Criteria

DISEASE CHARACTERISTICS:

Meets one of the following criteria:

Considered to be at increased risk for developing ovarian cancer, as defined by one of the following:

Has at least one first-degree relative (mother, sister, or daughter) with ovarian, primary peritoneal, or fallopian tube cancer
Has at least two first or second degree relatives diagnosed before age 50 with either ovarian, primary peritoneal, fallopian tube, and/or pancreatic cancer who have tested positive for hereditary cancer syndrome that includes an increased risk of gynecologic cancer (e.g., BRCA1/2 or Lynch Syndrome)or have increased risk as deemed by a certified genetic counselor
A personal or family history of a hereditary cancer syndrome that includes an increased risk of gynecologic cancer
Increased risk as deemed by a certified genetic counselor

Undergoing surgery for a gynecologic condition, including any of the following:

Diagnosis of a reproductive cancer
Benign gynecological condition (e.g., uterine leiomyomata, endometriosis, pelvic inflammatory disease, or follicular or corpus luteum ovarian cysts)
Highly suspicious adnexal mass
Risk-reducing prophylactic oophorectomy

PATIENT CHARACTERISTICS:

Age

Between the ages of 18 and 80

Study is for people with:

Ovarian Cancer

Estimated Enrollment:

6000

Study ID:

NCT00005095

Recruitment Status:

Recruiting

Sponsor:

Northwestern University

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There is 1 Location for this study

See Locations Near You

Robert H. Lurie Comprehensive Cancer Center at Northwestern University
Chicago Illinois, 60611, United States More Info
Clinical Trials Office - Robert H. Lurie Comprehensive Cancer
Contact
312-695-1301
[email protected]

How clear is this clinincal trial information?

Study is for people with:

Ovarian Cancer

Estimated Enrollment:

6000

Study ID:

NCT00005095

Recruitment Status:

Recruiting

Sponsor:


Northwestern University

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.