Ovarian Cancer Clinical Trial

Study of Oral ENMD-2076 Administered to Patients With Ovarian Cancer

Summary

The purpose of this study is to determine whether oral ENMD-2076 is effective in treatment of patients with platinum resistant ovarian, fallopian, or peritoneal cancer. Additional sites to be added.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Have histologically documented diagnosis of ovarian, fallopian or peritoneal cancer that is platinum resistant.
Have a pre-study echocardiogram or multigated acquisition (MUGA) scan with an actual left ventricular ejection fraction of greater than or equal to the institution lower limit of normal
Greater than or equal to 18 years of age
Have clinically acceptable laboratory screening results
Have an ECOG performance status of 0 or 1
Able to tolerate oral medications

Exclusion Criteria:

Have uncontrolled hypertension (systolic blood pressure greater than 150mmHg or diastolic blood pressure greater than 100mmHg); require two or more antihypertensive medications to control hypertension (including ACE inhibitors, beta blockers, calcium channel blockers, or diuretics)
Have chronic atrial fibrillation or QTc interval corrected for heart rate of greater than 470 msec
Have active, acute, or chronic clinically significant infections or bleeding
Have persistent 2+ protein by urinalysis or a history of nephrotic syndrome

Study is for people with:

Ovarian Cancer

Phase:

Phase 2

Estimated Enrollment:

64

Study ID:

NCT01104675

Recruitment Status:

Completed

Sponsor:

CASI Pharmaceuticals, Inc.

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There are 4 Locations for this study

See Locations Near You

University of Colorado Cancer Center
Aurora Colorado, 80045, United States
University of Chicago Medical Center
Chicago Illinois, 60637, United States
Indiana University Simon Cancer Center
Indianapolis Indiana, 46202, United States
Dana Farber/Partners Cancer Care
Boston Massachusetts, 02115, United States
Memorial Sloan-Kettering Cancer Center
New York New York, , United States
Princess Margaret Hospital
Toronto Ontario, , Canada

How clear is this clinincal trial information?

Study is for people with:

Ovarian Cancer

Phase:

Phase 2

Estimated Enrollment:

64

Study ID:

NCT01104675

Recruitment Status:

Completed

Sponsor:


CASI Pharmaceuticals, Inc.

How clear is this clinincal trial information?

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