Prostate Cancer Clinical Trial
Effects of Sulforaphane on Normal Prostate Tissue
Summary
The investigators proposed to identify the biological effects of a high-sulforaphane broccoli sprout extract in normal prostate tissue.
The investigators hypothesize that consumption of high-sulforaphane broccoli sprout extract every other day will inhibit growth of prostate cancer cells.
Eligibility Criteria
Inclusion Criteria:
Men aged 40-75 years
Low or intermediate grade prostate cancer (as defined by Gleason sum less than or equal to 7) and clinical stage T1 or T2
Serum Prostate specific antigen less than 20 ng/ml
Have elected radical prostatectomy, Brachytherapy or active surveillance as their primary treatment
Exclusion Criteria:
No current physician diagnosed disease (including but not limited to): kidney disease requiring dialysis, cognitive deficits, substance abuse
BMI < 18.5 kg/m2 or > 40 kg/m2
Use of any hormonal treatments, including but not limited to testosterone
Any previous cancer diagnosis or treatment within the previous five years, excluding non-melanoma skin cancer
Inability or unwillingness to eat a diet that is free of Brassica vegetables for the duration of the study
Use of any dietary supplements other than a multivitamin (including herbal preparations)
Allergy to cruciferous vegetables or any of the specific fillers used in the placebo
Usual consumption of > 5 servings per week of Brassica vegetables
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There is 1 Location for this study
Seattle Washington, 98108, United States
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