Laser Based Focal Ablation of Low Grade Prostate Cancer

Inclusion Criteria:

Male, 45 years of age or older
Diagnosis of prostate adenocarcinoma
Clinical stage T1c or T2a
Gleason score of 7 or less
A minimum of 12 biopsy cores sampled during diagnostic biopsy
Three or fewer biopsy cores with prostate cancer
No single biopsy core with greater than 50% of tumor involvement
A radiographically visible prostate lesion on MRI with concordance to biopsy sextant
A documented Karnofsky performance status of at least 70
Estimated survival of 20 years or greater, as determined by treating physician
Ability to give informed consent

Exclusion Criteria:

Previous surgery, radiation, or androgen deprivation therapy for prostate cancer
Presence of any condition (e.g., metal implant, shrapnel) not compatible with MRI
History of previous pelvic radiation
Severe lower urinary tract symptoms as measured by an International Prostate Symptom Score (IPSS) of 20 or greater. (See Appendix A)
History of other primary non-skin malignancy within previous three years