Prostate Cancer Clinical Trial

Multiparametric MRI in Evaluating Cancer Stage and Helping Treatment Planning in Patients With Prostate Cancer

Summary

This phase II trial studies how well multiparametric magnetic resonance imaging (MRI) works in evaluating cancer stage and helping treatment planning in patients with prostate cancer. Multiparametric MRI may be useful for evaluating the type of cancer in finding aggressive disease.

View Full Description

Full Description

PRIMARY OBJECTIVES:

I. To estimate the diagnostic performance as quantified by the area under the ROC curve to detect aggressive prostate cancer.

II. To develop a risk prediction model by incorporating overall PI-RADS, PSA, Gleason score and clinical stage to predict the presence of aggressive prostate cancer.

SECONDARY OBJECTIVES:

I. To evaluate the diagnostic performance of the individual PI-RADS score of each MRI parameter (T2W, DWI and DCE), as determined by local imaging review.

TERTIARY OBJECTIVES:

I. All clinical data including magnetic resonance (MR) images will be banked for future exploratory research aims.

OUTLINE:

Patients undergo mpMRI within 3 months prior to schedule surgery.

After completion of study, patients are followed up until radical prostatectomy pathology is reported and finalized.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Recently diagnosed with prostate cancer for whom definitive surgical treatment is indicated

Exclusion Criteria:

Not suitable to undergo MRI or receive gadolinium-based contrast agent (severe, untreatable claustrophobia; MRI-incompatible metallic objects or implanted medical devices; renal failure; weight greater than allowable by scanner per institutional standard practice)
Prior surgical and/or non-surgical treatment for prostate cancer
Prior hip replacement or other major pelvic surgery

Study is for people with:

Prostate Cancer

Estimated Enrollment:

852

Study ID:

NCT03697148

Recruitment Status:

Recruiting

Sponsor:

ECOG-ACRIN Cancer Research Group

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There are 39 Locations for this study

See Locations Near You

Mayo Clinic Hospital in Arizona
Phoenix Arizona, 85054, United States More Info
Site Public Contact
Contact
855-776-0015
Akira Kawashima
Principal Investigator
Mayo Clinic in Arizona
Scottsdale Arizona, 85259, United States More Info
Site Public Contact
Contact
855-776-0015
Akira Kawashima
Principal Investigator
Yale University
New Haven Connecticut, 06520, United States More Info
Site Public Contact
Contact
203-785-5702
[email protected]
Jeffrey C. Weinreb
Principal Investigator
University of Florida Health Science Center - Jacksonville
Jacksonville Florida, 32209, United States More Info
Site Public Contact
Contact
352-273-8675
[email protected]
Dheeraj Reddy Gopireddy
Principal Investigator
Mayo Clinic in Florida
Jacksonville Florida, 32224, United States More Info
Site Public Contact
Contact
855-776-0015
Akira Kawashima
Principal Investigator
Pali Momi Medical Center
'Aiea Hawaii, 96701, United States More Info
Site Public Contact
Contact
808-486-6000
Jeffrey L. Berenberg
Principal Investigator
Straub Pearlridge Clinic
'Aiea Hawaii, 96701, United States More Info
Site Public Contact
Contact
808-522-4333
Jeffrey L. Berenberg
Principal Investigator
Queen's Medical Center
Honolulu Hawaii, 96813, United States More Info
Site Public Contact
Contact
808-545-8548
Jeffrey L. Berenberg
Principal Investigator
Straub Clinic and Hospital
Honolulu Hawaii, 96813, United States More Info
Site Public Contact
Contact
808-522-4333
Jeffrey L. Berenberg
Principal Investigator
Midwestern Regional Medical Center
Zion Illinois, 60099, United States
Indiana University/Melvin and Bren Simon Cancer Center
Indianapolis Indiana, 46202, United States More Info
Site Public Contact
Contact
317-278-5632
[email protected]
Temel Tirkes
Principal Investigator
University of Iowa/Holden Comprehensive Cancer Center
Iowa City Iowa, 52242, United States More Info
Site Public Contact
Contact
800-237-1225
Maheen Rajput
Principal Investigator
University of Kansas Cancer Center
Kansas City Kansas, 66160, United States More Info
Site Public Contact
Contact
913-588-3671
[email protected]
William Parker
Principal Investigator
University of Kansas Hospital-Indian Creek Campus
Overland Park Kansas, 66211, United States More Info
Site Public Contact
Contact
913-588-3671
[email protected]
William Parker
Principal Investigator
East Jefferson General Hospital
Metairie Louisiana, 70006, United States More Info
Site Public Contact
Contact
504-210-3539
[email protected]
Scott E. Delacroix
Principal Investigator
LSU Healthcare Network / Metairie Multi-Specialty Clinic
Metairie Louisiana, 70006, United States More Info
Site Public Contact
Contact
504-210-3539
[email protected]
Scott E. Delacroix
Principal Investigator
Brigham and Women's Hospital
Boston Massachusetts, 02115, United States More Info
Site Public Contact
Contact
617-724-5200
Clare M. Tempany-Afdhal
Principal Investigator
Henry Ford Hospital
Detroit Michigan, 48202, United States More Info
Site Public Contact
Contact
313-916-3721
[email protected]
Haythem Y. Ali
Principal Investigator
Spectrum Health at Butterworth Campus
Grand Rapids Michigan, 49503, United States More Info
Site Public Contact
Contact
616-391-1230
[email protected]
Kathleen J. Yost
Principal Investigator
Henry Ford West Bloomfield Hospital
West Bloomfield Michigan, 48322, United States More Info
Site Public Contact
Contact
313-916-3721
[email protected]
Haythem Y. Ali
Principal Investigator
Mayo Clinic in Rochester
Rochester Minnesota, 55905, United States More Info
Site Public Contact
Contact
855-776-0015
Akira Kawashima
Principal Investigator
Washington University School of Medicine
Saint Louis Missouri, 63110, United States
Mercy Hospital Saint Louis
Saint Louis Missouri, 63141, United States More Info
Site Public Contact
Contact
314-251-7066
Jay W. Carlson
Principal Investigator
Dartmouth Hitchcock Medical Center
Lebanon New Hampshire, 03756, United States More Info
Site Public Contact
Contact
800-639-6918
[email protected]
Lawrence M. Dagrosa
Principal Investigator
NYP/Weill Cornell Medical Center
New York New York, 10065, United States More Info
Site Public Contact
Contact
212-746-1848
Scott T. Tagawa
Principal Investigator
Stony Brook University Medical Center
Stony Brook New York, 11794, United States More Info
Site Public Contact
Contact
800-862-2215
Marlene Zawin
Principal Investigator
UNC Lineberger Comprehensive Cancer Center
Chapel Hill North Carolina, 27599, United States More Info
Site Public Contact
Contact
877-668-0683
[email protected]
Ersan Altun
Principal Investigator
Rogue Valley Medical Center
Medford Oregon, 97504, United States More Info
Site Public Contact
Contact
541-789-4673
[email protected]
Liam C. Macleod
Principal Investigator
Penn State Milton S Hershey Medical Center
Hershey Pennsylvania, 17033, United States More Info
Site Public Contact
Contact
717-531-3779
[email protected]
Nabeel Sarwani
Principal Investigator
University of Pennsylvania/Abramson Cancer Center
Philadelphia Pennsylvania, 19104, United States More Info
Site Public Contact
Contact
800-474-9892
Mitchell D. Schnall
Principal Investigator
Thomas Jefferson University Hospital
Philadelphia Pennsylvania, 19107, United States More Info
Site Public Contact
Contact
215-600-9151
[email protected]
Edouard J. Trabulsi
Principal Investigator
Fox Chase Cancer Center
Philadelphia Pennsylvania, 19111, United States More Info
Site Public Contact
Contact
215-728-4790
Syed Yasir Andrabi
Principal Investigator
Vanderbilt University/Ingram Cancer Center
Nashville Tennessee, 37232, United States More Info
Site Public Contact
Contact
800-811-8480
Virginia Planz
Principal Investigator
MD Anderson in The Woodlands
Conroe Texas, 77384, United States More Info
Site Public Contact
Contact
866-632-6789
[email protected]
Tharakeswara Bathala
Principal Investigator
UT Southwestern/Simmons Cancer Center-Dallas
Dallas Texas, 75390, United States More Info
Site Public Contact
Contact
214-648-7097
[email protected]
Daniel N. Costa
Principal Investigator
M D Anderson Cancer Center
Houston Texas, 77030, United States More Info
Site Public Contact
Contact
877-632-6789
[email protected]
Tharakeswara Bathala
Principal Investigator
MD Anderson West Houston
Houston Texas, 77079, United States More Info
Site Public Contact
Contact
877-632-6789
[email protected]
Tharakeswara Bathala
Principal Investigator
MD Anderson League City
League City Texas, 77573, United States More Info
Site Public Contact
Contact
877-632-6789
[email protected]
Tharakeswara Bathala
Principal Investigator
Audie L Murphy VA Hospital
San Antonio Texas, 78229, United States More Info
Site Public Contact
Contact
877-469-5300
Michael A. Liss
Principal Investigator
University of Texas Health Science Center at San Antonio
San Antonio Texas, 78229, United States More Info
Site Public Contact
Contact
210-450-3800
[email protected]
Michael A. Liss
Principal Investigator
MD Anderson in Sugar Land
Sugar Land Texas, 77478, United States More Info
Site Public Contact
Contact
877-632-6789
[email protected]
Tharakeswara Bathala
Principal Investigator
West Virginia University Healthcare
Morgantown West Virginia, 26506, United States More Info
Site Public Contact
Contact
304-293-7374
[email protected]
Adam M. Luchey
Principal Investigator
ProHealth Waukesha Memorial Hospital
Waukesha Wisconsin, 53188, United States
UW Cancer Center at ProHealth Care
Waukesha Wisconsin, 53188, United States More Info
Site Public Contact
Contact
262-928-5539
[email protected]
Timothy R. Wassenaar
Principal Investigator

How clear is this clinincal trial information?

Study is for people with:

Prostate Cancer

Estimated Enrollment:

852

Study ID:

NCT03697148

Recruitment Status:

Recruiting

Sponsor:


ECOG-ACRIN Cancer Research Group

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.