Psoriasis Clinical Trial

A Prospective, Observational Study of Clinician and Patient-reported Outcomes in Patients With Dermatological Conditions

Summary

The primary goal of the study is to collect standardized patient and clinician reported outcome measures for patients diagnosed with a range of dermatological conditions in an academic clinical practice setting. By regularly measuring outcomes longitudinally in patients treated in a real-world setting, this study will provide valuable and necessary information as to the impact of both the disease and its treatments on patients over time and will inform the optimal clinical management of patients with living with dermatological disease.

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Full Description

The study is a multi-center, longitudinal, observational study to describe longitudinal trajectories of Clinician-Reported Outcomes (ClinROs) and Patient-Reported Outcomes (PROs) in patients with select dermatological conditions. This study will collect data using validated clinical instruments and patient-reported data on the disease course of alopecia areata (AA), atopic dermatitis (AD), hidradenitis suppurativa (HS), psoriasis (PsO), and vitiligo (VL), including symptom assessments and quality of life (QoL) measures from a patient perspective, to supplement routine clinical data collected from their healthcare providers. ClinRO data will be collected at baseline and routine follow-up visits for up to two years. PRO data will be collected directly from patients at baseline and at pre-specified follow-up time points (as defined in Tables 1 - 2e) for up to two years.

The objectives of this study are:

To describe longitudinal changes in disease activity, symptom control and both physical and mental HrQoL based on both ClinROs and PROs
To identify patient, disease and treatment factors associated with changes in PROs over time
To describe the association between PROs, ClinROs and clinical outcomes

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Adult (defined as the age of majority in their state of residence or older) at enrollment
Able to read and communicate in English
Have a smart phone or other internet enabled device capable of PRO data collection
Diagnosed with a qualifying, clinically confirmed, diagnosis of a study condition in the judgement of the treating physician at presentation
Willing and able to provide informed consent
Willing to participate in the collection of patient-reported outcomes for up to two years

Exclusion Criteria:

Current (or planned) participation in an interventional clinical trial where treatment and/or management of any of the study conditions is being dictated by a protocol.
Patient is not expected to be actively followed (i.e., seen at least annually as part of routine care) at the site for the duration of the follow-up period.

Study is for people with:

Psoriasis

Estimated Enrollment:

10000

Study ID:

NCT05084417

Recruitment Status:

Enrolling by invitation

Sponsor:

OM1, Inc.

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There is 1 Location for this study

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OM1
Boston Massachusetts, 02116, United States

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Study is for people with:

Psoriasis

Estimated Enrollment:

10000

Study ID:

NCT05084417

Recruitment Status:

Enrolling by invitation

Sponsor:


OM1, Inc.

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