Psoriasis Clinical Trial

Clinical Trial Finder Psoriasis Trials

A Study to Assess if Mirikizumab is Effective and Safe Compared to Secukinumab and Placebo in Moderate to Severe Plaque Psoriasis (OASIS-2)

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Summary

The reason for this study is to see how effective and safe mirikizumab is compared to secukinumab and placebo for moderate to severe plaque psoriasis.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Participant must have chronic plaque psoriasis for at least 6 months.

Exclusion Criteria:

Participant must not be breastfeeding or nursing woman.
Participant must not have had serious, opportunistic, or chronic/recurring infection within 3 months.
Participant must not have received a Bacillus Calmette-Guerin (BCG) vaccination within 12 months or received live vaccine(s) (including attenuated live vaccines) within 12 weeks of baseline or intend to receive either during the study.
Participant must not have any other skin conditions (excluding psoriasis).
Participant must not have previous exposure to Cosentyx and any other biologic therapy targeting IL-17 (including Taltz).
Participant must not have received anti-tumor necrosis factor (TNF) biologics within 8 weeks.
Participant must not have previous exposure to any biologic therapy targeting IL-23 (including Stelara).

Study is for people with:

Psoriasis

Phase:

Phase 3

Estimated Enrollment:

1484

Study ID:

NCT03535194

Recruitment Status:

Completed

Sponsor:

Eli Lilly and Company

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There are 174 Locations for this study

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University of Alabama at Birmingham
Birmingham Alabama, 35233, United States
Bakersfield Dermatology and Skin Cancer Medical Group
Bakersfield California, 93309, United States
David Stoll, M.D.
Beverly Hills California, 90212, United States
California Dermatology and Clinical Research Institute
Encinitas California, 92024, United States
Tien Q. Nguyen, MD inc. DBA First OC Dermatology
Fountain Valley California, 92708, United States
Keck School of Medicine University of Southern California
Los Angeles California, 90033, United States
Dermatology Clinical Trials
Newport Beach California, 92660, United States
San Luis Dermatology & Laser Clinic, Inc
San Luis Obispo California, 93405, United States
Clinical Science Institute
Santa Monica California, 90404, United States
Park Avenue Dermatology
Orange Park Florida, 32073, United States
Dermatologic Surgery Specialists, PC
Macon Georgia, 31217, United States
Medaphase Inc
Newnan Georgia, 30263, United States
Meridian Clinical Research
Savannah Georgia, 31406, United States
Treasure Valley Dermatology
Boise Idaho, 83713, United States
University Dermatology
Darien Illinois, 60561, United States
Arlington Dermatology
Rolling Meadows Illinois, 60008, United States
Dawes Fretzin Clinical Research
Indianapolis Indiana, 46250, United States
The Indiana Clinical Trials Center, PC
Plainfield Indiana, 46168, United States
The South Bend Clinic
South Bend Indiana, 46617, United States
Dermatology Specialist
Louisville Kentucky, 40241, United States
DelRicht Research
Baton Rouge Louisiana, 70809, United States
Dermatology and Skin Cancer Specialists
Rockville Maryland, 20850, United States
Lawrence J Green, M.D, LLC
Rockville Maryland, 20850, United States
ORA, Inc
Andover Massachusetts, 01810, United States
Central Dermatology PC
Saint Louis Missouri, 63117, United States
Psoriasis Treatment Center of Central New Jersey
East Windsor New Jersey, 08520, United States
Mount Sinai School of Medicine Dermatology Clinical Trials
New York New York, 10029, United States
PMG Research of Cary, LLC
Cary North Carolina, 27511, United States
University of North Carolina Dermatology and Skin Cancer Cen
Chapel Hill North Carolina, 27516, United States
PMG Research of Wilmington, LLC
Wilmington North Carolina, 28401, United States
Bexley Dermatology Research
Bexley Ohio, 43209, United States
University Hospitals Cleveland Medical Center
Cleveland Ohio, 44106, United States
Wright State Physicians Dermatology
Fairborn Ohio, 46435, United States
Oregon Dermatology and Research Center
Portland Oregon, 97210, United States
Oregon Health and Science University
Portland Oregon, 97239, United States
Clinical Partners LLC
Johnston Rhode Island, 02919, United States
Modern Research Associates PLLC
Dallas Texas, 75231, United States
Austin Institute for Clinical Research, Inc.
Pflugerville Texas, 78660, United States
Texas Dermatology and Laser Specialists
San Antonio Texas, 78218, United States
Jordan Valley Dermatology Center
West Jordan Utah, 84088, United States
Virginia Clinical Research
Norfolk Virginia, 23502, United States
Dermatology Associates
Seattle Washington, 98101, United States
CEDIC-Centro de Investigaciones Clinicas
Caba Buenos Aires, C1425, Argentina
Centro de Investigaciones Metabólicas (CINME)
Buenos Aires , C1027, Argentina
Buenos Aires Skin
Ciudad Autonoma Buenos Aires , C1055, Argentina
Instituto de Neumonología y Dermatología
Ciudad Autonoma Buenos Aires , C1425, Argentina
Psoriahue Medicina Interdisciplinaria
Ciudad Autonoma Buenos Aires , C1425, Argentina
Clinica Adventista de Belgrano
Ciudad Autonoma Buenos Aires , C1430, Argentina
Halitus Instituto Médico
Ciudad Autonoma de Buenos Aire , C1122, Argentina
Parra Dermatología
Mendoza , 5500, Argentina
Woden Dermatology
Phillip Australian Capital Territory, 2606, Australia
Veracity Clinical Research Pty Ltd
Woolloongabba Queensland, 4102, Australia
Clinical Trials SA Pty Ltd
Adelaide South Australia, 5073, Australia
Skin and Cancer Foundation Inc.
Carlton Victoria, 3053, Australia
Fremantle Dermatology
Perth Western Australia, 6160, Australia
Stratica Medical
Edmonton Alberta, T5K 1, Canada
Dr. Chih-ho Hong Medical Inc.
Surrey British Columbia, V3R 6, Canada
Eastern Canada Cutaneous Research Assoicates Ltd
Halifax Nova Scotia, B3H1Z, Canada
The Guenther Dermatology Research Centre
London Ontario, N6A 3, Canada
Lynderm Research Inc
Markham Ontario, L3P1X, Canada
SKiN Centre for Dermatology
Peterborough Ontario, K9J 5, Canada
K. Papp Clinical Research Inc
Waterloo Ontario, N2J 1, Canada
Innovaderm Research Inc
Montreal Quebec, H2X 2, Canada
Clintrial, s.r.o.
Praha 10 Hl. M. Praha, 100 0, Czechia
Fakultni nemocnice Kralovske Vinohrady
Praha 10 Hl. M. Praha, 100 3, Czechia
Fakultni Nemocnice U svate Anny
Brno Jihomoravský Kraj, 656 9, Czechia
Kozni ambulance Kutna Hora, s.r.o.
Kutna Hora Středočeský Kraj, 28430, Czechia
Krajska zdravotni a.s. - Masarykova nemocnice v Usti nad Labem, o.z.
Usti nad Labem Ustecký Kraj, 40113, Czechia
Kozni oddeleni
Novy Jicin , 741 0, Czechia
CHU Dupuytren 2
Limoges Cedex, 87042, France
CHU de Bordeaux Hopital Saint Andre
Bordeaux Cedex , 33075, France
CH du Mans - Pavillon Claude Monet
Le Mans Cedex 1 , 72037, France
Cabinet Médical
Martigues , 13500, France
Hopital Saint Eloi
Montpellier , 34295, France
CHU de Nice Hopital de L'Archet
Nice cedex 3 , 06202, France
Chu de Rouen Hopital Charles Nicolle
Rouen cedex , 76036, France
Hopital Larrey
Toulouse cedex 9 , 31059, France
Universitätsklinikum Heidelberg
Heidelberg Baden-Württemberg, 69120, Germany
Hautarztpraxis Dr. Leitz und Kollegen
Stuttgart Baden-Württemberg, 70178, Germany
Universitätsklinikum Tübingen
Tübingen Baden-Württemberg, 72076, Germany
Rosenpark Research Geschäftsbereich der Rosenparkklinik GmbH
Darmstadt Hessen, 64283, Germany
Klinikum der Johann Wolfgang Goethe-Universität Frankfurt
Frankfurt am Main Hessen, 60590, Germany
Dermatologisches Zentrum Osnabrück Nord
Bramsche Niedersachsen, 49565, Germany
Elbe Kliniken Stade Buxtehude GmbH Klinikum Buxtehude
Buxtehude Niedersachsen, 21614, Germany
Fachklinik Bad Bentheim
Bad Bentheim Nordrhein-Westfalen, 48455, Germany
Universitätsklinikum Schleswig-Holstein
Kiel Schleswig-Holstein, 24105, Germany
Universitätsklinikum Schleswig-Holstein
Lübeck Schleswig-Holstein, 23538, Germany
Klin. Forschung Berlin-Mitte GmbH
Berlin , 10117, Germany
Rothhaar Studien GmbH
Berlin , 10783, Germany
TFS Trial Form Support GmbH
Hamburg , 20537, Germany
Bacs-Kiskun Megyei Korhaz
Kecskemet Bacs-Kiskun, 6000, Hungary
Debreceni Egyetem Klinikai Kozpont Borgyogyaszati Klinika
Debrecen Hajdu-Bihar, 4032, Hungary
Trial Pharma Kft.
Puspokladany Hajdu-Bihar, 4150, Hungary
Allergo-Derm Bakos Kft
Szolnok Jasz-Nagykun-Szolnok, 5000, Hungary
UNO Medical Trials Kft.
Budapest , 1135, Hungary
Ambrozia Kft.
Budapest , 1238, Hungary
Oroshaza Varosi Onkormanyzat Korhaza
Oroshaza , 5900, Hungary
MedMare Bt
Veszprem , 8200, Hungary
Haemek Medical Center- Dermatology
Afula , 18341, Israel
Soroka Medical Center
Beer Sheva , 84101, Israel
Rambam Medical Center
Haifa , 35254, Israel
Rabin Medical Center
Petach Tikva , 49414, Israel
Sheba Medical Center
Ramat Gan , 52656, Israel
Tel Aviv Sourasky Medical Center
Tel Aviv , 64239, Israel
Istituto Clinico Humanitas
Rozzano Milano, 20089, Italy
Policlinico Univ. Agostino Gemelli
Roma Rome, 00168, Italy
Presidio Ospedaliero Firenze Centro Piero Palagi
Firenze , 50125, Italy
Policlinico di Tor Vergata
Roma , 00133, Italy
Nagoya City University Hospital
Nagoya Aichi, 467-8, Japan
Juntendo Urayasu Hospital
Urayasu Chiba, 279-0, Japan
Kurume University Hospital
Kurume Fukuoka, 830 0, Japan
Gunma University Hosptial
Maebashi Gunma, 371-8, Japan
Asahikawa Medical College Hospital
Asahikawa Hokkaido, 078-8, Japan
Tokyo Medical University Ibaraki Medical Center
Inashiki-gun Ibaraki, 300-0, Japan
Tokai University Hospital
Isehara Kanagawa, 259-1, Japan
Kyoto Prefectural University of Medicine
Kyoto-shi Kyoto, 602-8, Japan
Mie University Hospital
Tsu Mie, 514-8, Japan
Tohoku University Hospital
Sendai Miyagi, 980-8, Japan
Shinshu University Hospital
Matsumoto Nagano, 390-8, Japan
Ryukyu University Hospital
Nakagami-gun Okinawa, 903-0, Japan
Kansai Medical University Hospital
Hirakata Osaka, 573-1, Japan
Shiga University of Medical Science Hosptial
Ohtsu-shi Shiga, 520-2, Japan
The University of Tokyo Hospital
Bunkyo-ku Tokyo, 113-8, Japan
St. Lukes International Hospital
Chuo-Ku Tokyo, 104 8, Japan
Teikyo University Hospital
Itabashi-ku Tokyo, 173 8, Japan
Nihon University Itabashi Hospital
Itabashi-ku Tokyo, 173-8, Japan
Showa University Hospital
Shinagawa-ku Tokyo, 142-8, Japan
Tokyo Medical University Hospital
Shinjuku-ku Tokyo, 160-0, Japan
Yamaguchi University Hospital
Ube Yamaguchi, 755-8, Japan
Yamanashi Prefectural Central Hospital
Kofu Yamanashi, 400-8, Japan
Gifu University Hospital
Gifu , 501-1, Japan
Nagasaki University Hospital
Nagaski , 852-8, Japan
Osaka City University Hospital
Osaka , 545-8, Japan
Nippon Life Hospital
Osaka , 550-0, Japan
Tokushima University Hospital
Tokushima , 770-8, Japan
Wakayama MedicaL University Hospital
Wakayama , 641-8, Japan
Ilsan Paik Hospital
IlsanSeo-gu Goyang-si, 10380, Korea, Republic of
Seoul National University Bundang Hospital
Seongnam-si Gyeonggi-do, 13620, Korea, Republic of
Pusan National University Hospital
Busan Korea, 49241, Korea, Republic of
Gachon University Gil Medical Center
Incheon Korea, 21565, Korea, Republic of
Samsung Medical Center
Seoul Korea, 06351, Korea, Republic of
Korea University Guro Hospital
Seoul Korea, 08308, Korea, Republic of
Konkuk University Medical Center
Seoul , 05030, Korea, Republic of
Seoul St. Mary's Hospital
Seoul , 06591, Korea, Republic of
Chungang University Hospital
Seoul , 06973, Korea, Republic of
Severance Hospital Yonsei University Health System
Seoul , 120-7, Korea, Republic of
DermMEDICA Sp. z o.o.
Wroclaw Dolnoslaskie, 51-31, Poland
DermoDent, Centrum Medyczne Czajkowscy
Osielsko Kujawsko-pomorskie, 86-03, Poland
Dermed Centrum Medyczne Sp. z o.o.
Lodz Lodzkie, 90-26, Poland
Lubelskie Centrum Diagnostyczne
Swidnik Lubelskie, 21-04, Poland
Barbara Rewerska DIAMOND CLINIC
Krakow Malopolskie, 31-55, Poland
Centralny Szpital Kliniczny MSW Klinika Dermatologii
Warszawa Mazowieckie, 02-50, Poland
Centrum Medyczne Evimed
Warszawa Mazowieckie, 02-62, Poland
NZOZ ZDROWIE Osteo-Medic
Bialystok Podlaskie, 15-35, Poland
NZOZ Specjalistyczna Przychodnia Dermatologiczna Specderm
Bialystok Podlaskie, 15-37, Poland
Centrum Badan Klinicznych, PI House
Gdansk Pomorskie, 80-54, Poland
Centrum Medyczne Angelius Provita
Katowice Slaskie, 40-61, Poland
LASER CLINIC Specjalistyczne Gabinety Lekarskie
Szczecin Zachodniopomorskie, 70-33, Poland
Centrum Terapii Wspolczesnej J.M. Jasnorzewska S.K.A.
Lodz , 90-24, Poland
AI Centrum Medyczne
Poznan , 61-11, Poland
Santa Cruz Behavioral PSC
Bayamón , 00961, Puerto Rico
Office of Dr. Samuel Sanchez PSC
Caguas , 00727, Puerto Rico
Office of Dr. Alma M. Cruz
Carolina , 00985, Puerto Rico
Ponce School of Medicine CAIMED Center
Ponce , 00716, Puerto Rico
GCM Medical Group PSC
San Juan , 00917, Puerto Rico
Hospital Marina Baixa
Villajoyosa Alicante, 03570, Spain
Hospital Germans Trias i Pujol
Barcelona Badalona, 08916, Spain
Hospital de Manises
Manises Valencia, 46940, Spain
Hospital De Basurto
Bilbao Vizcaya, 48013, Spain
Hospital del Mar
Barcelona , 08003, Spain
Hospital Reina Sofia
Cordoba , 14004, Spain
Hospital Infanta Leonor
Madrid , 28031, Spain
Hospital Universitario Ramon y Cajal
Madrid , 28034, Spain
Hospital Universitario La Paz
Madrid , 28046, Spain
Centro de Especialidades Mollabao
Pontevedra , 36001, Spain
Hospital Universitario Virgen Macarena
Sevilla , 41009, Spain
Hospital Universitario La Fe de Valencia
Valencia , 46026, Spain
Salford Royal NHS Foundation Trust
Salford Greater Manchester, M6 8H, United Kingdom
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How clear is this clinincal trial information?

Study is for people with:

Psoriasis

Phase:

Phase 3

Estimated Enrollment:

1484

Study ID:

NCT03535194

Recruitment Status:

Completed

Sponsor:


Eli Lilly and Company

How clear is this clinincal trial information?

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