A Study to Evaluate Safety and Efficacy of PF-06826647 For Moderate To Severe Plaque Psoriasis

Inclusion Criteria:

Male or female between the ages of 18 and 75 years.
Participants with a diagnosis of plaque psoriasis (psoriasis vulgaris) for at least 6 months.
Have a PASI score of 12 or greater AND a Physician Global Assessment score of 3 (moderate) or 4 (severe).
Have plaque-type psoriasis covering at least 10 % of total body surface area (BSA).

Exclusion Criteria:

Have non-plaque forms of psoriasis.
Drug-induced psoriasis.
Current active infection.
Infected with Mycobacterium tuberculosis (TB).
Have any history of malignancies.
Require treatment with prohibited concomitant medications(s).
Positive for hepatitis B or C, or human immunodeficiency virus (HIV).