Psoriasis Clinical Trial
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of ABBV-157 in Healthy Volunteers and in Participants With Chronic Plaque Psoriasis
Summary
This is a study to evaluate pharmacokinetics (PK), safety and tolerability of ABBV-157 in healthy volunteers and in participants with chronic plaque psoriasis, and to evaluate the efficacy of ABBV-157 in the participants with psoriasis. This study consists of two substudies. Substudy 1 is a randomized, double-blind, placebo-controlled evaluation of multiple ascending oral doses of ABBV-157 in healthy adult volunteers. Substudy 2 is a randomized, double-blind, placebo-controlled study in which participants with moderate to severe chronic plaque psoriasis will be administered multiple oral doses of ABBV-157.
Eligibility Criteria
Inclusion Criteria:
Volunteer should be between 18 and 55 years of age and in general good health for Substudy 1 and participant with moderate to severe chronic plaque psoriasis between 18 and 75 years of age for Substudy 2 at the time of enrollment.
Participant should meet the laboratory assessments as mentioned in the protocol.
Exclusion Criteria:
Participant has a history of epilepsy, any significant cardiac, respiratory, renal, hepatic, gastrointestinal, opthalmologic, hematologic,or psychiatric disease or disorder, or any uncontrolled medical illness.
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There are 10 Locations for this study
Birmingham Alabama, 35205, United States
Phoenix Arizona, 85032, United States
Anaheim California, 92801, United States
Los Angeles California, 90045, United States
North Hollywood California, 91606, United States
Sandy Springs Georgia, 30328, United States
Grayslake Illinois, 60030, United States
Pittsburgh Pennsylvania, 15260, United States
Austin Texas, 78744, United States
Webster Texas, 77598, United States
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