Psoriasis Clinical Trial

Long-Term Follow-Up Study of Psoriasis Patients

Summary

The purpose of this study is to evaluate the long-term safety and profile of psoriasis patients who have completed participation in a previous study and who received treatment with MEDI-507.

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Full Description

This study will evaluate the long-term safety and lymphocyte repletion profile of psoriasis patients who have completed participation in a previous study and who received treatment with MEDI-507. Patients must have had an ALC > 30% lower than baseline (defined as baseline prior to any MEDI-507 exposure); or an absolute CD4 count of < 250 cells/uL. This study will also evaluate the development and durability of anti-MEDI-507 antibodies.

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Eligibility Criteria

Inclusion Criteria:

The patient has previously completed participation (i.e., completed per protocol, including any long term follow-up; or discontinued from the study due to withdrawal of consent, loss to follow-up, or other reason) in a Medimmune, Inc. study of MEDI-507 in psoriasis in which they received MEDI-507 (or placebo for patients who participated in a blinded placebo-controlled study of MEDI-507, and for whom the treatment assignment in that study has not been unblinded at the time of entry into this study)
The patient had an absolute lymphocyte count (ALC) > 30% lower than baseline (defined as baseline prior to any MEDI-507 exposure; or, for patients whose treatment assignments have not been unblinded at the time of entry into this study, drug exposure) at his/her final visit (excluding any long-term follow-up visits) in the most recent Medimmune, Inc. study in which the patient participated; or the patient had an absolute CD4 count of < 250 cells/uL at his/her final visit (including any protocol-specific long-term follow up) in the most recent Medimmune, Inc. study in which the patient participated.
Written informed consent obtained from the patient

Exclusion Criteria:

There are no exclusion criteria.

Study is for people with:

Psoriasis

Estimated Enrollment:

200

Study ID:

NCT00131066

Recruitment Status:

Completed

Sponsor:

MedImmune LLC

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There are 20 Locations for this study

See Locations Near You

Dermatology Research Clinic
Little Rock Arkansas, 72205, United States
Cherry Creek Dermatology
Denver Colorado, 80246, United States
Atlanta Dermatology, Vein & Research Center, LLC
Alpharetta Georgia, 30005, United States
Future Care Studies
Springfield Massachusetts, 72205, United States
Washington University, Dermatology Clinical Trials Unit
St. Louis Missouri, 63110, United States
VA Medical Center
Nashville Tennessee, 37212, United States
Northwest Kinetics
Tacoma Washington, 98405, United States
Universitaur Ziekenhuis Gent
Gent , 185, Belgium
CHU Centre Ville
Liege , 4020, Belgium
Capital District Health Authority, QE II Health Sciences Center
Halifax Nova Scotia, B3H1V, Canada
International Dermatology Research
Montreal Quebec, H3H1V, Canada
Innovaderm Research
Montreal , H2K 4, Canada
Hotel Dieu/Clinque Dermatologique
Nantes Cedex 1 , F-440, France
Hospital Saint-Louis Service de Dermatologie 1
Paris , F-754, France
Hospital Haut Leveque CHU Sud -Service de Dermatologie
Pessac , F-336, France
Universitataskilinkum der TU Dresden
Dresden , D-013, Germany
Universitatsklinikum Hautklinik
Dusseldorf , D-402, Germany
Klinikum de Johann - Wolfgang Goethe Universitate Frankfurt
Frankfurt , D-605, Germany
St. Urban, Dermatologie
Freiburg , D-791, Germany
Universitatsklinikum Hautklinik
Tubingen , D-720, Germany
Academisch Medisch Centrum/Universiteit van Amsterdam (AMC/UvA)
Amsterdam , 1105, Netherlands

How clear is this clinincal trial information?

Study is for people with:

Psoriasis

Estimated Enrollment:

200

Study ID:

NCT00131066

Recruitment Status:

Completed

Sponsor:


MedImmune LLC

How clear is this clinincal trial information?

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