Psoriasis Clinical Trial

Study To Evaluate Safety And Efficacy Of PF-06700841 In Subjects With Moderate To Severe Plaque Psoriasis

Summary

The purpose of this study is to determine whether PF-06700841 is safe and effective in the treatment of chronic plaque psoriasis.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Have had a diagnosis of plaque psoriasis (psoriasis vulgaris) for at least 6 months prior to Baseline/Day 1 (prior to first dose of study drug)
Have a PASI score of 12 or greater AND a PGA score of 3 ("moderate") or 4 ("severe") at Baseline/Day 1 (prior to first dose of study drug)
Have plaque-type psoriasis covering at least 10% of total body surface area (BSA) at Baseline/Day 1 (prior to first dose of study drug)
Considered by dermatologist investigator to be a candidate for systemic therapy or phototherapy of psoriasis (either naïve or history of previous treatment)

Exclusion Criteria:

Currently have non-plaque forms of psoriasis, eg, erythrodermic, guttate, or pustular psoriasis, with the exception of nail psoriasis which is allowed
Have evidence of skin conditions (eg, eczema) at the time of screening or baseline visit that would interfere with the evaluation of psoriasis
Cannot discontinue systemic therapies and/or topical therapies for the treatment of psoriasis and cannot discontinue phototherapy (UVB or PUVA)
Have previously been treated with Secukinumab (Cosentyx), and Ixekizumab (Taltz).
Have taken Apremilast (Otezla) within 3 months of first dose of study drug.
Have undergone treatment with tofacitinib within 3 months of first dose.

Study is for people with:

Psoriasis

Phase:

Phase 2

Estimated Enrollment:

212

Study ID:

NCT02969018

Recruitment Status:

Completed

Sponsor:

Pfizer

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There are 40 Locations for this study

See Locations Near You

Northwest Arkansas Clinical Trials Center, PLLC/Hull Dermatology, PA
Rogers Arkansas, 72758, United States
Anaheim Clinical Trials, LLC
Anaheim California, 92801, United States
California Dermatology & Clinical Research Institute
Encinitas California, 92024, United States
Emil A. Tanghetti, MD dba Center for Dermatology and Laser Surgery
Sacramento California, 95819, United States
Southern California Dermatology
Santa Ana California, 92701, United States
Tower Saint John's Imaging
Santa Monica California, 90403, United States
Clinical Science Institute
Santa Monica California, 90404, United States
Park Avenue Dermatology Administrative Annex
Orange Park Florida, 32073, United States
Park Avenue Dermatology
Orange Park Florida, 32073, United States
Olympian Clinical Research
Tampa Florida, 33609, United States
Rose Radiology
Tampa Florida, 33609, United States
Forward Clinical Trials, Inc
Tampa Florida, 33624, United States
Dundee Dermatology
West Dundee Illinois, 60118, United States
Dawes Fretzin Clinical Research Group, LLC
Indianapolis Indiana, 46256, United States
Dawes Fretzin Dermatology Group, LLC
Indianapolis Indiana, 46256, United States
Psoriasis Treatment Center of Central New Jersey
East Windsor New Jersey, 08520, United States
The Rockefeller University
New York New York, 10065, United States
Skin Search of Rochester, Inc.
Rochester New York, 14623, United States
Investigational Drug Services, UNC Hospitals
Chapel Hill North Carolina, 27514, United States
UNC Dermatology and Skin Cancer Center
Chapel Hill North Carolina, 27516, United States
UNC Clinical and Translation Research Center
Chapel Hill North Carolina, 27599, United States
Lynn Health Science Institute
Oklahoma City Oklahoma, 73112, United States
Vital Prospects Clinical Research Institute, P.C
Tulsa Oklahoma, 74136, United States
Health Concepts
Rapid City South Dakota, 57702, United States
Center for Clinical Studies
Houston Texas, 77004, United States
Lee Medical Associates, PA
San Antonio Texas, 78213, United States
Progressive Clinical Research, PA
San Antonio Texas, 78213, United States
Texas Dermatology and Laser Specialists
San Antonio Texas, 78218, United States
Virginia Clinical Research, Inc.
Norfolk Virginia, 23502, United States
Premier Clinical Research
Spokane Washington, 99202, United States
Wiseman Dermatology Research Inc.
Winnipeg Manitoba, R3M 3, Canada
Lynderm Research Inc
Markham Ontario, L3P 1, Canada
Research by ICLS
Oakville Ontario, L6J 7, Canada
Skin Centre for Dermatology
Peterborough Ontario, K9J 5, Canada
The Centre for Dermatology
Richmond Hill Ontario, L4B 1, Canada
K.Papp Clinical Research Inc.
Waterloo Ontario, N2J 1, Canada
Diex Research Sherbrooke Inc.
Sherbrooke Quebec, J1L 0, Canada
Centre de Recherche Dermatologique du Quebec metropolitain (CRDQ)
Quebec , G1V4X, Canada
Centrum Medyczne Enel-Med Przychodnia Grunwaldzka
Gdansk , 80-26, Poland
Centrum Badan Klinicznych PI-House Sp. z o.o.
Gdansk , 80-54, Poland
Dermoklinika Centrum Medyczne s.c. M.Kierstan, J. Narbutt, A. Lesiak
Lodz , 90-43, Poland
NZOZ "Nasz Lekarz" - Praktyka Grupowa Lekarzy Rodzinnych z Przychodnia Specjalistyczna
Torun , 87-10, Poland
MTZ Clinical Research Sp. z o.o.
Warszawa , 02-10, Poland
WroMedica s.c.
Wroclaw , 51-68, Poland

How clear is this clinincal trial information?

Study is for people with:

Psoriasis

Phase:

Phase 2

Estimated Enrollment:

212

Study ID:

NCT02969018

Recruitment Status:

Completed

Sponsor:


Pfizer

How clear is this clinincal trial information?

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