Acute Myeloid Leukemia Clinical Trial
Cytarabine in Combination With Arsenic Trioxide vs. Cytarabine Alone in Elderly Patients With Acute Myeloid Leukemia
Summary
The primary objective of this study is to determine whether low-dose cytarabine in combination with arsenic trioxide is more effective than low-dose cytarabine alone in achieving complete remission in elderly patients (≥60 years of age) with acute myeloid leukemia.
Eligibility Criteria
Inclusion Criteria:
The patient has confirmed acute myeloid leukemia (AML).
The patient is unwilling or unable to tolerate conventional induction chemotherapy.
The patient has no comorbid conditions that would limit life expectancy to less than 3 months.
Patient must meet specific laboratory parameters for study inclusion.
Exclusion Criteria:
- The patient has had previous cytotoxic chemotherapy for acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
Previous treatment with low-dose cytarabine is not permitted.
The patient has a QT interval outside of the protocol-specified range.
The patient has laboratory values outside of protocol-specified ranges.
The patient is concurrently treated with cytotoxic therapy, radiation, or investigational agents.
The patient has uncontrolled, severe cardiovascular or pulmonary disease or other uncontrolled medical condition.
The patient has known central nervous system involvement with AML.
Check Your Eligibility
Let’s see if you might be eligible for this study.
What is your age and gender ?
There are 12 Locations for this study
Los Angeles California, 90033, United States
Los Angeles California, 90095, United States
Chicago Illinois, 60612, United States
Indianapolis Indiana, 46202, United States
Buffalo New York, 14263, United States
New York New York, 10011, United States
New York New York, 10021, United States
Greenville North Carolina, 27834, United States
Oklahoma City Oklahoma, 73104, United States
Charleston South Carolina, 29425, United States
San Antonio Texas, 78229, United States
Toronto Ontario, M5G2M, Canada
How clear is this clinincal trial information?

Please confirm you are a US based health care provider:
Yes, I am a health care Provider No, I am not a health care providerSign Up Now.
Take Control of Your Disease Journey.
Sign up now for expert patient guides, personalized treatment options, and cutting-edge insights that can help you push for the best care plan.