Breast Cancer Clinical Trial

A Pilot Study of Bone Mineral Density in Postmenopausal Women After Treatment for Breast Cancer

Summary

The main purpose of this study is to see what levels of Bone Mineral Density post-menopausal women with breast cancer have, and to see if the level of Bone Mineral Density changes during a women's treatment after her surgery.

This trial studies changes in Bone Mineral Density and markers of of bone activity in post-menopausal women receiving treatment for early stage breast cancer.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Documented diagnosis of breast cancer
Last menstrual period occurring more than 5 years ago
Non-metastatic breast cancer tumor with the diagnosis of Tis, Tl-T4, N0-3, M0
DCIS is allowed, but LCIS (only) is not

Exclusion Criteria:

Any metabolic bone disease other than postmenopausal osteoporosis or osteopenia
Use of systemic gonadal hormonal medications or supplements within the past 24 months
Prior use of tamoxifen or raloxifene is permitted if the medication was discontinued more than 24 months prior to the diagnosis of breast cancer.
No adjuvant antiestrogen, antineoplastic, therapies are permitted on study.
Chronic use of systemic steroids for disease process other than breast cancer chemotherapy premedication or antiemetics
History of rheumatoid arthritis, ankylosing spondylitis, hyperparathyroidism, renal osteodystrophy, moderate to severe inflammatory or autoimmune disease or newly diagnosed thyroid condition requiring titration of medications.
Lobular carcinoma in situ or Stage IV breast cancer and patients with a concurrently active second malignancy other then adequately treated non-melanoma skin cancers or in situ cervical cancer.
participation in other clinical trials that are measuring BMD as a study parameter
Patients with conditions that are expected to distort BMD reading and make DEXA results unreliable
Patients with concurrent medical or psychiatric conditions that would keep them from understanding and complying with this clinical trial.

Study is for people with:

Breast Cancer

Estimated Enrollment:

9

Study ID:

NCT00399321

Recruitment Status:

Completed

Sponsor:

University of Michigan Rogel Cancer Center

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There is 1 Location for this study

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University of Michigan Comprehensive Cancer Center
Ann Arbor Michigan, 48109, United States

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Estimated Enrollment:

9

Study ID:

NCT00399321

Recruitment Status:

Completed

Sponsor:


University of Michigan Rogel Cancer Center

How clear is this clinincal trial information?

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