A Study Comparing Oral Picoplatin With Intravenous Picoplatin in Subjects With Solid Tumors

Inclusion Criteria:

Histological diagnosis of non-hematological malignancy.
Patients for whom no standard therapy exists and for whom, in the opinion of the investigator, treatments with single agent picoplatin is appropriate.
18 years of age or older.
ECOG performance status 0-2.
Life expectancy of at least 12 weeks.

(Additional inclusion criteria apply.)

Exclusion Criteria:

Symptomatic or uncontrolled brain metastases.
Prior radiation involving ≥ 30% of the total bone marrow space.
Any concurrent severe and/or uncontrolled medical conditions which could compromise participation in the study.
Gastrointestinal surgery that might interfere with absorption of orally administered drug.
Active inflammatory bowel disease, gastritis, ulcers, gastrointestinal or rectal bleeding.
Clinical evidence of pancreatic injury or active pancreatitis.
Female subjects who are pregnant or breastfeeding.

(Additional exclusion criteria apply.)