Breast Cancer Clinical Trial
A Study of Effect of Megakaryocytes and Platelets in Breast Cancer
Summary
Determining if Megakaryocytes and Platelets are Harmful or Helpful in Breast Cancer Cell Metastasis
Full Description
The purpose of this study is to determine how megakaryocytes (cells in the bone marrow responsible for making platelets, which are necessary for blood clotting) affect the survival and growth/division patterns of breast cancer stem cells, and the effects of breast cancer cells on megakaryocyte survival and function. Through chart review, the study team will look at the relationship between different blood components and different breast cancer diagnoses.
Eligibility Criteria
Inclusion Criteria:
Cohort 1-Biopsy negative
-Females age 18 and above
Cohort 2-Biopsy positive for carcinoma in situ (ductal, lobular, or other)
Females age 18 and above
Any subtype of breast cancer
Cohort 3-Biopsy positive for Stage 1, 2, or 3 invasive carcinoma (ductal, lobular, or other)
Females age 18 and above
Any subtype of breast cancer
Have no distant metastases
Cohort 4-Stage 4 Metastatic Disease
Females age 18 and above
Any subtype of breast cancer
Exclusion Criteria:
Cohort 1-Biopsy negative
Males
Females less than age 18
Cohort 2-Biopsy positive for carcinoma in situ (ductal, lobular, or other)
Males
Females less than age 18
Currently undergoing neoadjuvant therapy
Cohort 3-Biopsy positive for Stage 1, 2, or 3 invasive carcinoma (ductal, lobular, or other)
Males
Females less than age 18
Presence of distant metastases
Currently undergoing neoadjuvant therapy
Cohort 4-Stage 4 Metastatic Disease
Males
Females less than age 18
Currently undergoing neoadjuvant therapy
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There is 1 Location for this study
La Crosse Wisconsin, 54601, United States More Info
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Principal Investigator
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