Breast Cancer Clinical Trial
An Examination of Predictors of Indicators of Response to Letrozole 2.5 mg
Summary
To assess the quantitative real time PCR results of oligonucleotide probes for a number of gene transcription products that may be useful as predictors or indicators of response to letrozole
Full Description
To assess the quantitative real time PCR results of oligonucleotide probes for a number of gene transcription products (PCNA, cyclin-D1, ER alpha, PR, pS2, 450 aromatase, bcl-2, bax, caspase-3, and VEGFR) that may be useful as predictors or indicators of response to letrozole
Eligibility Criteria
Inclusion Criteria:
evidence of hyperplasia with/without atypia upon random periareolar fine needle aspiration of breast
on hormone replacement therapy
postmenopausal
increased risk of developing breast cancer based on personal or family history
never have taken aromatase inhibitors or selective estrogen receptor modulators in last six months
women who have a high risk of breast cancer
older than 18 years
Exclusion Criteria:
no anticoagulants
no marked breast tenderness
not pregnant or within twelve months of breast feeding/childbirth
Check Your Eligibility
Let’s see if you might be eligible for this study.
What is your age and gender ?
There is 1 Location for this study
Kansas City Kansas, 66160, United States
How clear is this clinincal trial information?