Breast Cancer Clinical Trial
Blood Sample Collection and Health Information Collection From Patients With Invasive Breast Cancer and Their Brothers and Sisters
RATIONALE: Collecting blood samples and health information from patients with invasive breast cancer and from their brothers and sisters over time may help the study of cancer in the future.
PURPOSE: This study is collecting blood samples and health information over time from patients with invasive breast cancer and from their brothers and sisters.
Collect blood samples and medical and background information from patients with invasive breast cancer and their affected or unaffected siblings.
OUTLINE: Patients and their siblings undergo blood collection. They also complete medical and background questionnaires.
Patients and their siblings are followed annually for 5 years.
PROJECTED ACCRUAL: A total of 1,000 patients and siblings will be accrued for this study.
Meets 1 of the following criteria:
Pathologically confirmed invasive breast cancer (patient)
No ductal carcinoma in situ
Affected OR unaffected sibling
Affected sibling must have had (or currently has) breast cancer only
Unaffected sibling must be female
No deceased siblings
Must be a full-blood related sibling
Patients receiving treatment on clinical trial ECOG-E1Y97 or ECOG-E3Y92 are not eligible
PRIOR CONCURRENT THERAPY:
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