Breast Cancer Clinical Trial
Chemotherapy Decisions and Outcomes in Older Women With Newly Diagnosed Breast Cancer
Summary
RATIONALE: Studying how older women make treatment decisions and how these decisions affect the outcome of treatment may help doctors plan more effective treatments and improve patient quality of life.
PURPOSE: This clinical trial is studying how a patient's treatment preferences and decisions about chemotherapy affect the outcome of treatment in older women with newly diagnosed breast cancer.
Full Description
OBJECTIVES:
Determine the relationship between preferences and chemotherapy decisions in women age 65 and over with operable, newly diagnosed breast cancer.
Determine how factors that could be targets for intervention affect the relationship between preferences and chemotherapy decisions in these patients.
Determine the relationships between preference-based chemotherapy decisions, quality of life, and satisfaction with treatment decisions in these patients.
Determine the disease-free survival and competing causes of mortality of these patients.
Determine the types of physician providers who care for older breast cancer survivors after initial cancer treatment is completed and explore how women decide about which physicians to see.
Measure quality indicators for the survivorship phase of care and evaluate if quality varies by type of physician provider model.
Determine if long-term patient-reported satisfaction varies as a function of physician model for providing follow-up care post-treatment.
Determine whether physician-patient communication and coordination of care after treatment ends mediate follow-up quality and outcomes post-treatment.
OUTLINE: This is a cohort study.
Patients participate in interviews over 30-45 minutes at baseline, at 6 months, and at 1 and 2 years.
Patients are followed annually for at least 5 years.
PROJECTED ACCRUAL: A total of 1,296 patients will be accrued for this study within 18-24 months.
Eligibility Criteria
DISEASE CHARACTERISTICS:
Histologically confirmed primary adenocarcinoma of the breast
Operable disease
Invasive and unilateral tumor
No more than 20 weeks since diagnosis
T1-4 (tumor size ≥ 1 cm), N0, M0 OR
T1-4, N1-3, M0
No prior carcinoma in situ, lobular carcinoma in situ, ductal carcinoma in situ, or invasive breast cancer
Hormone receptor status:
Any estrogen receptor status
PATIENT CHARACTERISTICS:
Age
65 and over
Sex
Female
Other
No other malignancy except those for which the patient has completed treatment AND is considered to be at less than 30% risk of recurrence
History of non-melanoma skin cancer allowed
Sufficient cognitive function to consent to and complete interviews
English or Spanish speaking
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There are 77 Locations for this study
Mountain View California, 94040, United States
Palo Alto California, 94301, United States
Pismo Beach California, 93449, United States
Greenwich Connecticut, 06830, United States
Washington, D.C. District of Columbia, 20010, United States
Washington, D.C. District of Columbia, 20307, United States
Lake Worth Florida, 33461, United States
Chicago Illinois, 60637, United States
Chicago Illinois, 60640, United States
La Grange Illinois, 60525, United States
Rockford Illinois, 61108, United States
Elkhart Indiana, 46514, United States
Elkhart Indiana, 46514, United States
Elkhart Indiana, 46515, United States
Kokomo Indiana, 46904, United States
La Porte Indiana, 46350, United States
Merrillville Indiana, 46410, United States
Mishawaka Indiana, 46545, United States
Mishawaka Indiana, 46545, United States
Plymouth Indiana, 46563, United States
South Bend Indiana, 46601, United States
South Bend Indiana, 46601, United States
South Bend Indiana, 46617, United States
Westville Indiana, 46391, United States
Scarborough Maine, 04074, United States
Baltimore Maryland, 21237, United States
Attleboro Massachusetts, 02703, United States
Boston Massachusetts, 02114, United States
Boston Massachusetts, 02115, United States
Boston Massachusetts, 02115, United States
Gloucester Massachusetts, 01930, United States
Hyannis Massachusetts, 02601, United States
Lowell Massachusetts, 01854, United States
Battle Creek Michigan, 49017, United States
Big Rapids Michigan, 49307, United States
Grand Rapids Michigan, 49503, United States
Grand Rapids Michigan, 49503, United States
Grand Rapids Michigan, 49503, United States
Muskegon Michigan, 49443, United States
Niles Michigan, 49120, United States
Saint Joseph Michigan, 49085, United States
Saint Joseph Michigan, 49085, United States
Traverse City Michigan, 49684, United States
Wyoming Michigan, 49519, United States
Chesterfield Missouri, 63017, United States
Columbia Missouri, 65203, United States
Saint Louis Missouri, 63110, United States
Saint Louis Missouri, 63128, United States
Grand Island Nebraska, 68803, United States
North Platte Nebraska, 69103, United States
Omaha Nebraska, 68198, United States
Las Vegas Nevada, 89102, United States
Las Vegas Nevada, 89106, United States
Concord New Hampshire, 03301, United States
Exeter New Hampshire, 03833, United States
Hooksett New Hampshire, 03106, United States
Laconia New Hampshire, 03246, United States
Lebanon New Hampshire, 03756, United States
Manchester New Hampshire, 03102, United States
Manchester New Hampshire, 03103, United States
Nashua New Hampshire, 03060, United States
Nashua New Hampshire, 03060, United States
Livingston New Jersey, 07039, United States
Buffalo New York, 14263, United States
East Syracuse New York, 13057, United States
Jamaica New York, 11432, United States
New York New York, 10065, United States
Rochester New York, 14621, United States
Chapel Hill North Carolina, 27599, United States
Durham North Carolina, 27710, United States
Fayetteville North Carolina, 28302, United States
Henderson North Carolina, 27536, United States
Lumberton North Carolina, 28359, United States
Oxford North Carolina, 27565, United States
Pinehurst North Carolina, 28374, United States
Raleigh North Carolina, 27609, United States
Roxboro North Carolina, 27573, United States
Washington North Carolina, 27889, United States
Beaufort South Carolina, 29902, United States
Columbia South Carolina, 29210, United States
Myrtle Beach South Carolina, 29572, United States
Berlin Corners Vermont, 05602, United States
Burlington Vermont, 05401, United States
Fairfax Virginia, 22031, United States
Huntington West Virginia, 25702, United States
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