Breast Cancer Clinical Trial

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Summary

Earlier detection of disease recurrence will enable greater treatment options and has strong potential to improve patient outcomes. This project is translational and has the potential to lead to future translational research opportunities, including interventional trials in which therapeutic escalation is offered at the early circulating tumor DNA (ctDNA) molecular residual disease (MRD) detection timepoint. Ultimately, the integration of ctDNA into the clinical workflow has the potential to enhance cancer diagnosis, treatment, surveillance, and prognosis, and guide clinical decision-making in this era of personalized precision medicine.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Eligible healthy donors will be at least 18 years of age.

Exclusion Criteria:

Healthy donors younger than 18 years of age

Study is for people with:

Breast Cancer

Estimated Enrollment:

100

Study ID:

NCT04354064

Recruitment Status:

Recruiting

Sponsor:

Washington University School of Medicine

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There is 1 Location for this study

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Washington University School of Medicine
Saint Louis Missouri, 63110, United States More Info
Russell Pachynski, M.D.
Contact
314-286-2341
[email protected]
Russell Pachynski, M.D.
Principal Investigator
Peter Harris, Ph.D.
Sub-Investigator
Re-I Chin, M.D.
Sub-Investigator
Hiram Gay, M.D.
Sub-Investigator
Mackenzie Daly, M.D.
Sub-Investigator
Wade Thorstad, M.D.
Sub-Investigator
Jose Zevallos, M.D., MPH
Sub-Investigator
Sidharth Puram, M.D., Ph.D.
Sub-Investigator
Varun Puri, M.D.
Sub-Investigator
Christopher Maher, Ph.D.
Sub-Investigator
Ha Dang, Ph.D.
Sub-Investigator
Aadel Chaudhuri, M.D., Ph.D.
Sub-Investigator
Paul Jones, B.A.
Sub-Investigator
Benjamin Tan, M.D.
Sub-Investigator
James Hsieh, M.D., Ph.D.
Sub-Investigator
Zachary Smith, M.D.
Sub-Investigator
Eric Kim, M.D.
Sub-Investigator
Vivek Arora, M.D.
Sub-Investigator
Brian Van Tine, M.D., Ph.D.
Sub-Investigator
Angela Hirbe, M.D., Ph.D.
Sub-Investigator
Matthew Spraker, M.D., Ph.D.
Sub-Investigator
Cynthia Ma, M.D., Ph.D.
Sub-Investigator
Imran Zoberi, M.D.
Sub-Investigator
Ryan Fields, M.D.
Sub-Investigator
Koushik Das, M.D.
Sub-Investigator
Ricardo Ramirez, M.D.
Sub-Investigator
David Chen, M.D., Ph.D.
Sub-Investigator
Nicholas Semenkovich, M.D., Ph.D.
Sub-Investigator

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Estimated Enrollment:

100

Study ID:

NCT04354064

Recruitment Status:

Recruiting

Sponsor:


Washington University School of Medicine

How clear is this clinincal trial information?

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