Breast Cancer Clinical Trial

Determining Molecular Drivers of Radiation Dermatitis

Summary

This study is being conducted to address key gaps in current knowledge and set the stage for rational design of strategies to prevent (pre-exposure to radiation), mitigate (post-exposure to radiation before overt signs/symptoms appear), and/or treat (post-onset of signs/symptoms) radiation dermatitis (itchy, dry skin or a rash on swollen, reddened skin).

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Patients receiving standard-of-care postoperative radiation therapy (2-2.7 Gy per fraction) to the breast and/or chest wall for breast cancer treatment.
Tissue diagnosis of breast cancer.
Age > 18 years
Signed informed consent.
Complete blood count within normal limits within the preceding 2 weeks.

Exclusion criteria:

Induction chemotherapy or biologic therapy
Concurrent chemotherapy or biologic therapy
Autoimmune disease with skin manifestations - psoriasis, dermatomyositis, scleroderma, eczema, polymyositis
Allergy to lidocaine anesthesia
Known bleeding diathesis (anticoagulation with warfarin, coagulation/bleeding disorders, vitamin C or K deficiency, thrombocytopenia)
History of keloids or easy scarring

Study is for people with:

Breast Cancer

Estimated Enrollment:

20

Study ID:

NCT04764682

Recruitment Status:

Recruiting

Sponsor:

Mayo Clinic

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There is 1 Location for this study

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Mayo Clinic
Jacksonville Florida, 32224, United States

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Estimated Enrollment:

20

Study ID:

NCT04764682

Recruitment Status:

Recruiting

Sponsor:


Mayo Clinic

How clear is this clinincal trial information?

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