Breast Cancer Clinical Trial

Diversity and Inclusion in Research Underpinning Prevention and Therapy Trials

Summary

This proposal brings together multidisciplinary teams from four New York City institutions charged with reducing cancer disparities that affect approximately two million people residing in some of the most diverse and underserved communities in the United States. The intent of this collaborative research is captured by its acronym, DISRUPT: Diversity & IncluSion in Research Underpinning Prevention & Therapy Trials. To disrupt the norms that maintain heightened risk and poorer outcomes experienced by BIPOC, the research team propose three integrated and synergistic aims to improve diversity and inclusion in CTs through disruptive approaches at the community (Aim 1), provider, system and patient (Aim 2), and basic and translational scientist levels (Aim 3). All three aims focus on metrics for changing norms reified in institutional policies and established practice that will provide essential evidence to translate and scale these changes to institutions and networks involved in cancer treatment research. In Aim 1, the research team will partner with local organizations to formulate and disseminate new norms regarding cancer care and research and diffuse these new norms throughout the community via community organizations and Health Ambassadors bringing a different vantage point on CTs, raising awareness and increasing demand for access to cancer research. In Aim 2, the research team will create an electronic approach to identify key clinical characteristics of patients and trials and match patients and trials and bring these data to patients and their physicians at the time of key decisions. In Aim 3, the research team will provide and integrate essential experiential training in diversity, social determinants of health and the importance of conducting community-relevant work into basic and translational science training. This DISRUPT proposal provides the foundation to disrupt norms about cancer clinical trials in our communities, delivery systems and scientific research enterprises.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

All patients >21 years of age with invasive breast, prostate or liver cancer, who face a treatment decision
patients of doctors who have consented to participate
able to give consent and speak either English or Spanish will be eligible to participate.
For provider recruitment, oncologists, and advanced practitioners caring for patients with breast, prostate, liver cancer including medical, surgical, radiation oncologists, interventional radiologists, urologists & hepatologists.

Exclusion Criteria:

Patients who are unable to give consent
unable to understand English or Spanish
lack of invasive breast/prostate/liver cancer
those who do not face an imminent treatment decision

Study is for people with:

Breast Cancer

Estimated Enrollment:

1705

Study ID:

NCT05146297

Recruitment Status:

Not yet recruiting

Sponsor:

Icahn School of Medicine at Mount Sinai

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There are 3 Locations for this study

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Albert Einstein College of Medicine
Bronx New York, 10461, United States More Info
Ariana Tao
Contact
Bruce Rapkin
Principal Investigator
Icahn School of Medicine at Mount Sinai
New York New York, 10029, United States More Info
Radhi Yagnik
Contact
[email protected]
Nina Bickell
Principal Investigator
Herbert Irving Comprehensive Cancer Care Center
New York New York, 10032, United States More Info
Kimberly Burke
Contact
Mary Beth Terry
Principal Investigator

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Estimated Enrollment:

1705

Study ID:

NCT05146297

Recruitment Status:

Not yet recruiting

Sponsor:


Icahn School of Medicine at Mount Sinai

How clear is this clinincal trial information?

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