Breast Cancer Clinical Trial
Epothilone (Ixabepilone) Plus Capecitabine Versus Capecitabine Alone in Patients With Advanced Breast Cancer
Summary
The purpose of this clinical research study is to learn if BMS-247550 added to the approved therapy of capecitabine (Xeloda) provides measurable clinical benefits over capecitabine alone in women with metastatic breast cancer. Patients should have previously received an anthracycline and a taxane. The safety of this treatment will also be studied.
Eligibility Criteria
Patients must have received prior treatment which included both an anthracycline (i.e., doxorubicin or epirubicin) and a taxane (i.e., paclitaxel or docetaxel).
Patients must have received no more than two prior chemotherapy regimens. Patients who have not received treatment for metastatic disease must have relapsed within one year.
Patients may not have any history of brain and/or leptomeningeal metastases.
Patients may not have Grade 2 or worse neuropathy at the time of study entry.
Patients may not have had prior treatment with any epothilones and/or capecitabine (i.e. Xeloda)
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There is 1 Location for this study
Tucson Arizona, , United States
Beverly Hills California, , United States
Corona California, , United States
Hartford Connecticut, , United States
Plantation Florida, , United States
Boise Idaho, , United States
Evanston Illinois, , United States
Iowa City Iowa, , United States
Louisville Kentucky, , United States
Baton Rouge Louisiana, , United States
Bethesda Maryland, , United States
Boston Massachusetts, , United States
Jackson Mississippi, , United States
Columbia Missouri, , United States
Voorhees New Jersey, , United States
Albuquerque New Mexico, , United States
Bronx New York, , United States
Latham New York, , United States
Mineola New York, , United States
New York New York, , United States
Durham North Carolina, , United States
Goldsboro North Carolina, , United States
Hickory North Carolina, , United States
Kinston North Carolina, , United States
Canton Ohio, , United States
Columbus Ohio, , United States
Langhorne Pennsylvania, , United States
Knoxville Tennessee, , United States
Memphis Tennessee, , United States
Dallas Texas, , United States
Charlottesville Virginia, , United States
Norfolk Virginia, , United States
Richmond Virginia, , United States
Marshfield Wisconsin, , United States
Avelianeda Buenos Aires, , Argentina
Bahia Blanca Buenos Aires, , Argentina
Ciudad Autonoma De Buenos Aires Buenos Aires, , Argentina
Escobar Buenos Aires, , Argentina
Resistencia Chaco, , Argentina
Barrio Alto Verde Cordoba, , Argentina
San Miguel De Tucuman Tucuman, , Argentina
Buenos Aires , , Argentina
Mendoza , , Argentina
Salta , , Argentina
Santa Fe , , Argentina
Sydney New South Wales, , Australia
Westmead New South Wales, , Australia
Brisbane Queensland, , Australia
Herston Queensland, , Australia
South Brisbane Queensland, , Australia
Toowoomba Queensland, , Australia
Adelaide South Australia, , Australia
Woodville South Australia, , Australia
East Melbourne Victoria, , Australia
Parkville Victoria, , Australia
Perth Western Australia, , Australia
Graz , , Austria
Voecklabruck , , Austria
Wien , , Austria
Bruxelles , , Belgium
Charleroi , , Belgium
Gent , , Belgium
Hasselt , , Belgium
Kortrijk , , Belgium
Wilrijk , , Belgium
Centro-Porto Alegre Rio Grande Do Sul, , Brazil
Bela Vista Sao Paulo, , Brazil
Higienopolis Sao Paulo, , Brazil
Sao Paulo Sp, , Brazil
Rio De Janeiro , , Brazil
Thunder Bay Ontario, , Canada
Montreal Quebec, , Canada
Santiago Metropolitana, , Chile
Beijing Beijing, , China
Guangzhou Guangdong, , China
Nanjing Jiangsu, , China
Dalian Liaoning, , China
Dilian Liaoning, , China
Jinan Shandong, , China
Shanghai Shanghai, , China
Xi'An Shanxi, , China
Hangzhou Zhejiang, , China
Split , , Croatia
Zagreb , , Croatia
Brno , , Czechia
Hradec Kralove , , Czechia
Prague 5 , , Czechia
Prague , , Czechia
Aalborg , , Denmark
Herlev , , Denmark
Kobenhavn O , , Denmark
Angers , , France
Bordeaux , , France
Caen , , France
Clermont-Ferrand , , France
Colmar , , France
Le Mans , , France
Metz , , France
Paris Cedex 13 , , France
Pierre Benite , , France
Reims , , France
Saint Brieuc , , France
Saint Gregoire , , France
Saint Herblain , , France
Tours Cedex , , France
Villejuif Cedex , , France
Berlin , , Germany
Erlangen , , Germany
Essen , , Germany
Hannover , , Germany
Karlsruhe , , Germany
Kiel , , Germany
Marburg , , Germany
Munchen , , Germany
Rehling , , Germany
Saarbrucken , , Germany
Tubingen , , Germany
Ulm , , Germany
Wiesbaden , , Germany
Athens , , Greece
Crete , , Greece
Patras , , Greece
Thessaloniki , , Greece
Wilton Cork, , Ireland
Cork , , Ireland
Dublin 8 , , Ireland
Dublin 9 , , Ireland
Dublin , , Ireland
Galway , , Ireland
Haifa , , Israel
Jerusalem , , Israel
Ramat-Gan , , Israel
Tel Aviv , , Israel
Rozzano Milan, , Italy
Bari , , Italy
Firenze , , Italy
Genova , , Italy
Milano , , Italy
Modena , , Italy
Perugia , , Italy
Potenza , , Italy
Roma , , Italy
San Giovanni Rotondo , , Italy
Sora , , Italy
Torino , , Italy
Gyeonggi-Do , , Korea, Republic of
Incheon , , Korea, Republic of
Seoul , , Korea, Republic of
Arnhem , , Netherlands
Den Haag , , Netherlands
Enschede , , Netherlands
Zwolle , , Netherlands
Coimbra , , Portugal
Lisboa , , Portugal
Kazan , , Russian Federation
Moscow , , Russian Federation
St. Petersburg , , Russian Federation
Singapore , , Singapore
Port Elizabeth Eastern Cape, , South Africa
Johannesburg Gauteng, , South Africa
Pretoria Gauteng, , South Africa
Panorama Western Cape, , South Africa
Terassa Barcelona, , Spain
Barcelona , , Spain
Cadiz , , Spain
Cordoba , , Spain
Elche (Alicante) , , Spain
Hospitalet De Llobregat , , Spain
Jaen , , Spain
Madrid , , Spain
Pontevedra , , Spain
Reus , , Spain
Salamanca , , Spain
Sevilla , , Spain
Tenerife , , Spain
Valencia , , Spain
Zaragoza , , Spain
Bern , , Switzerland
Thun , , Switzerland
Zurich , , Switzerland
Taipei , , Taiwan
Ankara , , Turkey
Istanbul , , Turkey
Izmir , , Turkey
Belfast Armagh, , United Kingdom
Glasgow Central, , United Kingdom
London Greater London, , United Kingdom
Shrewsbury Shropshire, , United Kingdom
Birmingham West Midlands, , United Kingdom
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