Breast Cancer Clinical Trial

Epothilone (Ixabepilone) Plus Capecitabine Versus Capecitabine Alone in Patients With Advanced Breast Cancer

Summary

The purpose of this clinical research study is to learn if BMS-247550 added to the approved therapy of capecitabine (Xeloda) provides measurable clinical benefits over capecitabine alone in women with metastatic breast cancer. Patients should have previously received an anthracycline and a taxane. The safety of this treatment will also be studied.

View Eligibility Criteria

Eligibility Criteria

Patients must have received prior treatment which included both an anthracycline (i.e., doxorubicin or epirubicin) and a taxane (i.e., paclitaxel or docetaxel).
Patients must have received no more than two prior chemotherapy regimens. Patients who have not received treatment for metastatic disease must have relapsed within one year.
Patients may not have any history of brain and/or leptomeningeal metastases.
Patients may not have Grade 2 or worse neuropathy at the time of study entry.
Patients may not have had prior treatment with any epothilones and/or capecitabine (i.e. Xeloda)

Study is for people with:

Breast Cancer

Phase:

Phase 3

Estimated Enrollment:

1221

Study ID:

NCT00082433

Recruitment Status:

Completed

Sponsor:

R-Pharm

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There is 1 Location for this study

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Tucson Arizona, , United States
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Beverly Hills California, , United States
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Corona California, , United States
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Hartford Connecticut, , United States
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Plantation Florida, , United States
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Boise Idaho, , United States
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Evanston Illinois, , United States
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Iowa City Iowa, , United States
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Louisville Kentucky, , United States
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Jackson Mississippi, , United States
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Voorhees New Jersey, , United States
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Bronx New York, , United States
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Mineola New York, , United States
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Canton Ohio, , United States
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Langhorne Pennsylvania, , United States
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Escobar Buenos Aires, , Argentina
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Enschede , , Netherlands
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Zwolle , , Netherlands
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Coimbra , , Portugal
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Kazan , , Russian Federation
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Port Elizabeth Eastern Cape, , South Africa
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Pretoria Gauteng, , South Africa
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Terassa Barcelona, , Spain
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Elche (Alicante) , , Spain
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Hospitalet De Llobregat , , Spain
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Glasgow Central, , United Kingdom
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London Greater London, , United Kingdom
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Shrewsbury Shropshire, , United Kingdom
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Birmingham West Midlands, , United Kingdom

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Phase:

Phase 3

Estimated Enrollment:

1221

Study ID:

NCT00082433

Recruitment Status:

Completed

Sponsor:


R-Pharm

How clear is this clinincal trial information?

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