The specific aims of this study are to determine the efficacy and cost-effectiveness of a weight loss program compared with usual care (control) treatment on 6-month changes in body weight, body fat, serum hormones, and breast tissue markers associated with prognosis in breast cancer survivors.
We will conduct a two-armed study comparing a combination of an in-person and telephone weight loss program compared to usual care/wait list in 100 breast cancer survivors. Women will be randomized into one of the study arms using a random permuted block design. Research staff collecting body composition data, as well as reviewing forms and entering data, will be blinded to the participant's study group.
American Joint Committee on Cancer (AJCC) Stages 0-IIIC Breast Cancer BMI >25 kg/m2 Completed surgery, chemotherapy and radiation at least 2 months ago Physically able to exercise Agrees to be randomly assigned to either weight loss or control Gives informed consent to participate in all study activities Able to come for baseline and 6-month clinic visits Mentally competent
