Breast Cancer Clinical Trial

Monitoring the Response of Chemotherapy on Breast Cancer Tumor by Photon Migration Spectroscopy

Summary

Optimal management of patients with locally advanced breast cancer remains a complex therapeutic problem. Newly diagnosed breast cancers in the United States with a higher incidence in medically underserved areas. The optimal intensity and duration of neoadjuvant chemotherapy still remains controversial due to the difficulty of evaluating response to therapy. The goal would be to prevent over and under treatment of patients with neoadjuvant chemotherapy.

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Full Description

The Researcher developed a diagnostic device called Diffuse Optical Spectroscopy Imaging is a non-invasive optical technique that utilizes intensity-modulated, near-infrared light to quantitatively measure optical properties in thick tissues.

Diffuse Optical Spectroscopy Imaging can images tissue hemoglobin , oxygen saturation, blood volume fraction, water content, fat content and cellular structure. The measurements provide quantitative optical property values that reflect changes in tissue perfusion, oxygen consumption, and cell/matrix development.

There is no therapeutic benefit to the subject, especially none that might influence the indication for the diagnostic procedure as indicated. However, information obtained may lead to a new form of non-invasive imaging for the early detection of breast cancer.

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Eligibility Criteria

Inclusion Criteria:

Female non-pregnant and age greater than or equal to 21 years old but less than 75 years old
Diagnosed with breast cancer and will be receiving neoadjuvant chemotherapy

Exclusion Criteria:

Female pregnant and age less than 21 years old and have no diagnosis of breast cancer

Study is for people with:

Breast Cancer

Estimated Enrollment:

77

Study ID:

NCT00540852

Recruitment Status:

Completed

Sponsor:

University of California, Irvine

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There are 2 Locations for this study

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Beckman Laser Institute University Of California Irvine
Irvine California, 92612, United States
Chao Family Comprehensive Cancer Center
Orange California, 92868, United States

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Study is for people with:

Breast Cancer

Estimated Enrollment:

77

Study ID:

NCT00540852

Recruitment Status:

Completed

Sponsor:


University of California, Irvine

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